Notch signaling is an evolutionarily highly conserved signaling mechanism, but in contrast to
signaling pathways such as Wnt, Sonic Hedgehog, and BMP/TGF-β, Notch signaling occurs …

Salivary glands are essential structures in the oral cavity. A variety of diseases, such as
cancer, autoimmune diseases, infections and physical traumas, can alter the functionality of …

BACKGROUND Adenoid cystic carcinoma (ACC) is a rare malignancy arising in salivary
glands and other sites, characterized by high rates of relapse and distant spread …

Purpose: Salivary gland adenoid cystic carcinoma (ACC) has heterogeneous clinical
behavior. Currently, all patients are treated uniformly, and no standard-of-care systemic …

Salivary gland neoplasms are a morphologically heterogenous group of lesions that are
often diagnostically challenging. In recent years, considerable progress in salivary gland …

Adenoid cystic carcinoma (ACC) is an aggressive salivary gland malignancy with limited
treatment options for recurrent or metastatic disease. Due to chemotherapy resistance and …

Simple Summary Diagnosing salivary gland neoplasms (SGN) remain a challenge, given
their underlying biological nature and overlapping features. Evolving techniques in …

Salivary gland neoplasms are an uncommon and widely heterogeneous group of tumors. In
recent years, there has been considerable progress in efforts to reveal the molecular …

Simple Summary Patients with adenoid cystic carcinoma (ACC) often experience late distant
metastasis years after definitive therapy, most commonly to the lungs. Currently, there is little …

Simple Summary Adenoid cystic carcinoma (ACC) is an aggressive glandular cancer with
poor prognosis that preferentially occurs in the head and neck. The MYB and MYBL1 …