Depression is the leading cause of disability around the world, but little is known about its
pathology. Currently, the diagnosis of depression is made based on clinical manifestations …

Longitudinal comorbidity of depression and cognitive impairment has been reported by
number of epidemiological studies but the underlying mechanisms explaining the link …

Structural and functional brain alterations are common in patients with major depressive
disorder (MDD). In this review, we assessed the recent literature (1995–2018) on the …

In modern society, depression is one of the most common mental illness; however, its
pathophysiology is not yet fully understood. A great body of evidence suggests that …

Worldwide, the incidence of major depressive disorder (MDD) is increasing annually,
resulting in greater economic and social burdens. Moreover, the pathological mechanisms …

The high inter-individual heterogeneity in individuals with depression limits neuroimaging
studies with case-control approaches to identify promising biomarkers for individualized …

Internalizing disorders encompass anxiety, fear and depressive disorders, which exhibit
overlap at both conceptual and symptom levels. Given that a neurobiological evaluation is …

Background: The findings of many neuroimaging studies in patients with first-episode major
depressive disorder (MDD), and even those of previous meta-analysis, are divergent. To …

Background Probiotics are suggested to improve depressive symptoms via the microbiota-
gut-brain axis. We have recently shown a beneficial clinical effect of probiotic …

Background As a neuroprogressive illness, depression is accompanied by brain structural
abnormality that extends to many brain regions. However, the progressive structural …