Obesity and early-onset colorectal cancer risk: emerging clinical evidence and biological mechanisms

P Xu, Z Tao, H Yang, C Zhang - Frontiers in Oncology, 2024 - frontiersin.org
Early-onset colorectal cancer (EOCRC) is indicated as a global burden. EOCRC The
disease is associated with specific molecular and clinical features. As Obesity is a well …

[HTML][HTML] Early-onset/young-onset colorectal carcinoma: a comparative analysis of morphological features and biomarker profile

AA Hashmi, M Aslam, K Rashid, AH Ali, TU Dowlah… - Cureus, 2023 - ncbi.nlm.nih.gov
Methods This was a retrospective study conducted at the Department of Histopathology,
Liaquat National Hospital, Karachi, Pakistan. A total of 254 biopsy-proven cases of CRC …

Identification of differentially expressed genes and splicing events in early-onset colorectal cancer

OM Marx, MM Mankarious, WA Koltun… - Frontiers in …, 2024 - frontiersin.org
The incidence of colorectal cancer (CRC) has been steadily increasing in younger
individuals over the past several decades for reasons that are incompletely defined …

[HTML][HTML] Association of KRAS Mutation and Gene Pathways in Colorectal Carcinoma: A Transcriptome- and Methylome-Wide Study and Potential Implications for …

F Jasmine, A Almazan, Y Khamkevych… - International Journal of …, 2024 - mdpi.com
Kirsten Rat Sarcoma (KRAS) is the most commonly mutated oncogene in colorectal
carcinoma (CRC). We have previously reported the interactions between microsatellite …

A competing risk nomogram to predict cancer-specific mortality of patients with late-onset colorectal cancer

Z Liao, Y Deng, J Zhou, J Zhu, R Xia - Journal of Cancer Research and …, 2023 - Springer
Objective This study aimed to compare the clinical characteristics and survival differences
between early-onset colorectal cancer (EOCRC) patients and late-onset colorectal cancer …

Pathways Related to Colon Inflammation Are Associated with Colorectal Carcinoma: A Transcriptome-and Methylome-Wide Study

MG Kibriya, F Jasmine, J Pekow, A Munoz, C Weber… - Cancers, 2023 - mdpi.com
Simple Summary Colon cancer is one of the common cancers affecting a large number of
patients globally. In sporadic CRC, several genetic factors may play important roles such as …