Near‐infrared stimulation of the auditory nerve: A decade of progress toward an optical cochlear implant
PD Littlefield, CP Richter - Laryngoscope investigative …, 2021 - Wiley Online Library
Objectives We provide an appraisal of recent research on stimulation of the auditory system
with light. In particular, we discuss direct infrared stimulation and ongoing controversies …
with light. In particular, we discuss direct infrared stimulation and ongoing controversies …
[HTML][HTML] Emerging trends in the development of flexible optrode arrays for electrophysiology
Optical-electrode (optrode) arrays use light to modulate excitable biological tissues and/or
transduce bioelectrical signals into the optical domain. Light offers several advantages over …
transduce bioelectrical signals into the optical domain. Light offers several advantages over …
Thermal effects on neurons during stimulation of the brain
All electric and magnetic stimulation of the brain deposits thermal energy in the brain. This
occurs through either Joule heating of the conductors carrying current through electrodes …
occurs through either Joule heating of the conductors carrying current through electrodes …
Thermal block of action potentials is primarily due to voltage-dependent potassium currents: a modeling study
Objective. Thermal block of action potential conduction using infrared lasers is a new
modality for manipulating neural activity. It could be used for analysis of the nervous system …
modality for manipulating neural activity. It could be used for analysis of the nervous system …
Selective inhibition of small-diameter axons using infrared light
Novel clinical treatments to target peripheral nerves are being developed which primarily
use electrical current. Recently, infrared (IR) light was shown to inhibit peripheral nerves …
use electrical current. Recently, infrared (IR) light was shown to inhibit peripheral nerves …
Single infrared light pulses induce excitatory and inhibitory neuromodulation
The excitatory and inhibitory effects of single and brief infrared (IR) light pulses (2 µm) with
millisecond durations and various power levels are investigated with a custom-built fiber …
millisecond durations and various power levels are investigated with a custom-built fiber …
Stimulation of water and calcium dynamics in astrocytes with pulsed infrared light
AI Borrachero‐Conejo, WR Adams… - The FASEB …, 2020 - Wiley Online Library
Astrocytes are non‐neuronal cells that govern the homeostatic regulation of the brain
through ions and water transport, and Ca2+‐mediated signaling. As they are tightly …
through ions and water transport, and Ca2+‐mediated signaling. As they are tightly …
Infrared neural stimulation fails to evoke neural activity in the deaf guinea pig cochlea
At present there is some debate as to the processes by which infrared neural stimulation
(INS) activates neurons in the cochlea, as the lasers used for INS can potentially generate a …
(INS) activates neurons in the cochlea, as the lasers used for INS can potentially generate a …
Heat pulse excitability of vestibular hair cells and afferent neurons
RD Rabbitt, AM Brichta… - Journal of …, 2016 - journals.physiology.org
In the present study we combined electrophysiology with optical heat pulse stimuli to
examine thermodynamics of membrane electrical excitability in mammalian vestibular hair …
examine thermodynamics of membrane electrical excitability in mammalian vestibular hair …
Identifying optimal parameters for infrared neural stimulation in the peripheral nervous system
Significance: Infrared neural stimulation (INS) utilizes pulsed infrared light to selectively elicit
neural activity without exogenous compounds. Despite its versatility in a broad range of …
neural activity without exogenous compounds. Despite its versatility in a broad range of …