Chronic pain after traumatic brain injury: pathophysiology and pain mechanisms

KA Irvine, JD Clark - Pain medicine, 2018 - academic.oup.com
Background Traumatic brain injury refers to a broad range of neurological, cognitive, and
emotional factors that result from the application of an external force to the head. Individuals …

Minimal traumatic brain injury causes persistent changes in DNA methylation at BDNF gene promoters in rat amygdala: a possible role in anxiety-like behaviors

S Sagarkar, T Bhamburkar, G Shelkar… - Neurobiology of …, 2017 - Elsevier
Minimal traumatic brain injury (MTBI) often transforms into chronic neuropsychiatric
conditions including anxiety, the underlying mechanisms of which are largely unknown. In …

Modeling chronic traumatic encephalopathy: the way forward for future discovery

RC Turner, BP Lucke-Wold, AF Logsdon… - Frontiers in …, 2015 - frontiersin.org
Despite the extensive media coverage associated with the diagnosis of chronic traumatic
encephalopathy (CTE), our fundamental understanding of the disease pathophysiology …

[HTML][HTML] Sex-specific effects of cytotoxic chemotherapy agents cyclophospha-mide and mitomycin C on gene expression, oxidative DNA damage, and epigenetic …

A Kovalchuk, R Rodriguez-Juarez, Y Ilnytskyy… - Aging (Albany …, 2016 - ncbi.nlm.nih.gov
Recent research shows that chemotherapy agents can be more toxic to healthy brain cells
than to the target cancer cells. They cause a range of side effects, including memory loss …

A closed-body preclinical model to investigate blast-induced spinal cord injury

C Norris, J Weatherbee, S Murphy… - Frontiers in Molecular …, 2023 - frontiersin.org
Blast-induced spinal cord injuries (bSCI) are common and account for 75% of all combat-
related spinal trauma. It remains unclear how the rapid change in pressure contributes to …

Transcriptional and epigenetic regulation in injury-mediated neuronal dendritic plasticity

Y Wang, WY Li, ZG Li, LX Guan, LX Deng - Neuroscience bulletin, 2017 - Springer
Injury to the nervous system induces localized damage in neural structures and neuronal
death through the primary insult, as well as delayed atrophy and impaired plasticity of the …

A moderate blast exposure results in dysregulated gene network activity related to cell death, survival, structure, and metabolism

KA Edwards, V Motamedi, ND Osier, HS Kim… - Frontiers in …, 2020 - frontiersin.org
Blast exposure is common in military personnel during training and combat operations, yet
biological mechanisms related to cell survival and function that coordinate recovery remain …

[PDF][PDF] Prevention and reversal of Alzheimer's disease

RN Kostoff, Y Zhang, J Ma, AL Porter… - Georgia Institute of …, 2017 - core.ac.uk
Prevention and Reversal of Alzheimer's Disease Copyright © 2017 Ronald N. Kostoff et al 1
PREVENTION AND REVERSAL OF AL Page 1 Prevention and Reversal of Alzheimer's Disease …

Epigenetic Mechanisms in Blast-Induced Neurotrauma

ZS Bailey - 2017 - vtechworks.lib.vt.edu
Blast-induced neurotrauma (BINT) is a prevalent brain injury within both military and civilian
populations due to current engagement in overseas conflict and ongoing terrorist events …

[图书][B] Elucidating and Pharmacologically Targeting Secondary Injury Cascades following Neural Injury

BP Lucke-Wold - 2016 - search.proquest.com
4 million concussions occur each year in the United States. Recent evidence suggests that
some of these individuals are susceptible to neurodegenerative disease development …