The thalamus is a complex neural structure with numerous anatomical subdivisions and
intricate connectivity patterns. In recent decades, the traditional view of the thalamus as a …

Cerebral small vessel disease (cSVD) is a frequent finding in imaging of the brain in older
adults, especially in the concomitance of cardiovascular disease risk factors. Despite the …

The link between white matter hyperintensities (WMH) and cortical thinning is thought to be
an important pathway by which WMH contributes to cognitive deficits in cerebral small …

BACKGROUND: White matter hyperintensities (WMH) are associated with cognitive
dysfunction after ischemic stroke. Yet, uncertainty remains about affected domains, the role …

Abstract Background White matter hyperintensities (WMHs) are often measured globally, but
spatial patterns of WMHs could underlie different risk factors and neuropathological and …

BACKGROUND: Lacunes are associated with cognitive impairment. We sought to identify
strategic lacune locations associated with mild cognitive impairment (MCI) and subtypes of …

The best solution continues to be prevention and preservation of brain health. Brain health is
defined as “optimal capacity to function adaptively in the environment” by the American …

INTRODUCTION We assessed whether co‐morbid small vessel disease (SVD) has clinical
predictive value in preclinical or prodromal Alzheimer's disease. METHODS In 1090 non …

Background: Post-stroke cognitive impairment (PSCI) occurs in up to 50% of stroke
survivors. Presence of pre-existing vascular brain injury, in particular the extent of white …

Hypotension is a leading cause of age-related cognitive impairment. The available literature
evidences that vascular factors are associated with dementia and that hypotension alters …