Recent successes in heart failure treatment

CSP Lam, KF Docherty, JE Ho, JJV McMurray… - Nature Medicine, 2023 - nature.com
Remarkable recent advances have revolutionized the field of heart failure. Survival has
improved among individuals with heart failure and a reduced ejection fraction and for the …

Heart failure with preserved ejection fraction

CE Hamo, C DeJong, N Hartshorne-Evans… - Nature Reviews …, 2024 - nature.com
Heart failure with preserved ejection fraction (HFpEF) accounts for nearly half of all heart
failure cases and has a prevalence that is expected to rise with the growing ageing …

Anthropometric measures and adverse outcomes in heart failure with reduced ejection fraction: revisiting the obesity paradox

JH Butt, MC Petrie, PS Jhund, N Sattar… - European heart …, 2023 - academic.oup.com
Aims Although body mass index (BMI) is the most commonly used anthropometric measure,
newer indices such as the waist-to-height ratio, better reflect the location and amount of …

Association of transthyretin Val122Ile variant with incident heart failure among black individuals

V Parcha, G Malla, MR Irvin, ND Armstrong, SE Judd… - Jama, 2022 - jamanetwork.com
Importance A genetic variant in theTTRgene (rs76992529; Val122Ile), present more
commonly in individuals with African ancestry (population frequency: 3%-4%), causes …

Levels of TNF-α and soluble TNF receptors in normal-weight, overweight and obese patients with dilated non-ischemic cardiomyopathy: does Anti-TNF therapy still …

E Lazar-Poloczek, E Romuk, W Jacheć, W Stanek… - Biomedicines, 2022 - mdpi.com
Background. We sought to measure the levels of adipokines, TNF-α and soluble receptors
(sTNFr1, sTNFr2) in heart failure patients with reduced ejection fraction (HFrEF) due to non …

Prognosis of a malignant phenotype of obesity defined by a cardiac biomarker in hypertension: the Japan Morning Surge-Home Blood Pressure study

H Watanabe, S Hoshide, H Kanegae, K Kario - Hypertension Research, 2024 - nature.com
Obesity with increased high-sensitive cardiac troponin T (hs-cTnT) has been reported to be
more likely to progress cardiovascular disease (CVD) events, which suggests that hs-cTnT …

Effect of body mass index on N-terminal pro-brain natriuretic peptide values in patients with heart failure

T Ha Manh, D Do Anh, T Le Viet - The Egyptian Heart Journal, 2023 - Springer
Background N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a biomarker used for
the diagnosis of heart failure. There is a relationship between NT-proBNP levels and body …

The multidimensional value of natriuretic peptides in heart failure, integrating laboratory and clinical aspects

D Gruson, A Hammerer-Lercher… - Critical Reviews in …, 2024 - Taylor & Francis
Natriuretic peptides (NP) play an essential role in heart failure (HF) regulation, and their
measurement has improved diagnostic and prognostic accuracy. Clinical symptoms and …

Longitudinal NT‐proBNP: Associations With Echocardiographic Changes and Outcomes in Heart Failure

K Teramoto, WT Tay, J Tromp… - Journal of the …, 2024 - Am Heart Assoc
Background The relationship of serial NT‐proBNP (N‐terminal pro‐B‐type natriuretic
peptide) measurements with changes in cardiac features and outcomes in heart failure (HF) …

Clinical implications of the universal definition for the prevention and treatment of heart failure

C Chandramouli, S Stewart, W Almahmeed… - Clinical …, 2022 - Wiley Online Library
The diagnosis of heart failure (HF) primarily relies on signs and symptoms that are neither
sensitive nor specific. This impedes timely diagnosis and delays effective therapies or …