Peritoneal adhesions (PA) are a postoperative syndrome with high incidence rate, which
can cause chronic abdominal pain, intestinal obstruction, and female infertility. Previous …

Simple Summary We review the value of large animal models for improving the translation of
biomedical research for human application, focusing primarily on sheep. Abstract An …

Our knowledge about the gut microbiota of pigs is still scarce, despite the importance of
these animals for biomedical research and agriculture. Here, we present a collection of …

Gastrointestinal disease is a prevalent cause of morbidity and mortality and the use of
animal models have been instrumental in studying mechanisms of digestive …

Background The microbiome alterations are associated with cancer growth and may
influence the immune system and response to therapy. Particularly, the gut microbiome has …

The intestinal microbiota and its metabolites appear to be an important factor for
gastrointestinal function and health. However, research is still needed to further elaborate …

The gastrointestinal tract is a key source of superoxide so as to be one of the most
vulnerable to oxidative stress damage. Ellagic acid (EA), a polyphenol displays widely …

The community of microorganisms in the mammalian gastrointestinal tract, referred to as the
gut microbiota, influences host physiology and immunity. The last decade of microbiome …

An important practical limitation of the three-dimensional geometry of stem-cell derived
intestinal organoids is that it prevents easy access to the apical epithelium for testing food …

Swine is biologically one of the most relevant large animal models for biomedical research.
With its use as food animal that can be exploited as a free cell and tissue source for research …