Glucose as a major antioxidant: when, what for and why it fails?

A Cherkas, S Holota, T Mdzinarashvili, R Gabbianelli… - Antioxidants, 2020 - mdpi.com
A human organism depends on stable glucose blood levels in order to maintain its
metabolic needs. Glucose is considered to be the most important energy source, and …

4-Hydroxynonenal in redox homeostasis of gastrointestinal mucosa: implications for the stomach in health and diseases

A Cherkas, N Zarkovic - Antioxidants, 2018 - mdpi.com
Maintenance of integrity and function of the gastric mucosa (GM) requires a high
regeneration rate of epithelial cells during the whole life span. The health of the gastric …

Aging affects insulin resistance, insulin secretion, and glucose effectiveness in subjects with normal blood glucose and body weight

LY Huang, CH Liu, FY Chen, CH Kuo, P Pitrone, JS Liu - Diagnostics, 2023 - mdpi.com
Aim: Several studies have demonstrated that factors including diabetes, including insulin
resistance (IR), glucose effectiveness (GE), and the first and second phase of insulin …

An exploratory study of physiological and biochemical parameters to identify simple, robust and relevant biomarkers for therapeutic interventions for PTSD: study …

V Serhiyenko, K Holzmann, S Holota… - Proceeding of the …, 2022 - mspsss.org.ua
Introduction. The incidence of post-traumatic stress disorder (PTSD) is increasing due to war
in Ukraine is of growing importance as this disorder is a serious risk factor for alcohol/drug …

Amaranth oil reduces accumulation of 4-hydroxynonenal-histidine adducts in gastric mucosa and improves heart rate variability in duodenal peptic ulcer patients …

A Cherkas, K Zarkovic, A Cipak Gasparovic… - Free radical …, 2018 - Taylor & Francis
Helicobacter pylori-induced oxidative stress in gastric mucosa (GM) is a milieu for the
development of chronic gastritis, duodenal peptic ulcer (DPU), gastric cancer, and a number …

A comparative study between current and past Helicobacter pylori infection in terms of microalbuminuria in patients with type 2 diabetes

HM Ahmad, HS Al-Fishawy, I Shaltout… - BMC Infectious …, 2024 - Springer
Abstract Background The prevalence of Helicobacter pylori (H. pylori) infection and its
potential relationship to various diseases is currently a focus of attention. The aim of this …

A Helicobacter pylori-associated insulin resistance in asymptomatic sedentary young men does not correlate with inflammatory markers and urine levels of 8-iso-PGF2 …

A Cherkas, S Golota, F Guéraud… - … of Physiology and …, 2018 - Taylor & Francis
A potential contribution of H. pylori contamination to low-grade inflammation, oxidative stress
(OS) and insulin resistance as well as correlations between these parameters in …

[PDF][PDF] Synthesis and in vivo evaluation of pyrazoline-thiazolidin-4-one hybrid Les-5581 as a potential non-steroidal anti-inflammatory agent

SM Holota, HO Derkach, IL Demchuk… - Biopolymers and …, 2019 - researchgate.net
Aim. Synthesis and in vivo study of acute toxicity, anti-inflammatory (anti-exudative) activity
and side effects of pyrazoline-thiazolidin-4-one hybrid Les-5581 under conditions of …

Highly purified calf hemodialysate (Actovegin®) may improve endothelial function by activation of proteasomes: A hypothesis explaining the possible mechanisms of …

A Stelmakh, O Abrahamovych, A Cherkas - Medical hypotheses, 2016 - Elsevier
Highly purified calf hemodialysate (HPCH) known as Actovegin® or Solcoseryl® is one of
the most controversial drugs currently marketed worldwide. It is not registered as drug in …

Synthesis and diuretic activity of novel 5-amino-1, 3, 4-thiadiazole-2-thiol derivatives

IV Drapak, BS Zimenkovsky, MV Slabyy, SM Holota… - 2021 - dspace.nuph.edu.ua
To summarize, in an attempt to obtain an efficacious and non-toxic diuretic, we have
designed and synthesized a series of 1, 3, 4-thia-diazole-bearing derivatives. Some …