Recombinant protein vaccines, a proven approach against coronavirus pandemics
With the COVID-19 pandemic now ongoing for close to a year, people all over the world are
still waiting for a vaccine to become available. The initial focus of accelerated global …
still waiting for a vaccine to become available. The initial focus of accelerated global …
[HTML][HTML] Comparative safety of vaccine adjuvants: a summary of current evidence and future needs
N Petrovsky - Drug safety, 2015 - Springer
Use of highly pure antigens to improve vaccine safety has led to reduced vaccine
immunogenicity and efficacy. This has led to the need to use adjuvants to improve vaccine …
immunogenicity and efficacy. This has led to the need to use adjuvants to improve vaccine …
Developments in vaccine adjuvants
FZ Firdaus, M Skwarczynski, I Toth - Vaccine Design: Methods and …, 2022 - Springer
Vaccines, including subunit, recombinant, and conjugate vaccines, require the use of an
immunostimulator/adjuvant for maximum efficacy. Adjuvants not only enhance the strength …
immunostimulator/adjuvant for maximum efficacy. Adjuvants not only enhance the strength …
Severe acute respiratory syndrome-associated coronavirus vaccines formulated with delta inulin adjuvants provide enhanced protection while ameliorating lung …
Y Honda-Okubo, D Barnard, CH Ong, BH Peng… - Journal of …, 2015 - Am Soc Microbiol
Although the severe acute respiratory syndrome-associated coronavirus (SARS-CoV)
epidemic was controlled by nonvaccine measures, coronaviruses remain a major threat to …
epidemic was controlled by nonvaccine measures, coronaviruses remain a major threat to …
[HTML][HTML] Flaviviruses in Europe: complex circulation patterns and their consequences for the diagnosis and control of West Nile disease
C Beck, MA Jimenez-Clavero, A Leblond… - International journal of …, 2013 - mdpi.com
In Europe, many flaviviruses are endemic (West Nile, Usutu, tick-borne encephalitis viruses)
or occasionally imported (dengue, yellow fever viruses). Due to the temporal and …
or occasionally imported (dengue, yellow fever viruses). Due to the temporal and …
Immunogenicity and safety of SpikoGen®, an adjuvanted recombinant SARS‐CoV‐2 spike protein vaccine as a homologous and heterologous booster vaccination: a …
P Tabarsi, N Anjidani, R Shahpari… - …, 2022 - Wiley Online Library
SpikoGen® is a subunit recombinant spike protein vaccine combined with Advax‐CpG55.
2™ adjuvant. This COVID‐19 vaccine was shown to be safe, immunogenic and efficacious …
2™ adjuvant. This COVID‐19 vaccine was shown to be safe, immunogenic and efficacious …
[HTML][HTML] Usutu virus: an emerging flavivirus in Europe
Usutu virus (USUV) is an African mosquito-borne flavivirus belonging to the Japanese
encephalitis virus serocomplex. USUV is closely related to Murray Valley encephalitis virus …
encephalitis virus serocomplex. USUV is closely related to Murray Valley encephalitis virus …
Advax™, a novel microcrystalline polysaccharide particle engineered from delta inulin, provides robust adjuvant potency together with tolerability and safety
N Petrovsky, PD Cooper - Vaccine, 2015 - Elsevier
There is an ongoing need for new adjuvants to facilitate development of vaccines against
HIV, tuberculosis, malaria and cancer, amongst many others. Unfortunately, the most potent …
HIV, tuberculosis, malaria and cancer, amongst many others. Unfortunately, the most potent …
[HTML][HTML] Prefusion RSV F immunization elicits Th2-mediated lung pathology in mice when formulated with a Th2 (but not a Th1/Th2-balanced) adjuvant despite …
KM Eichinger, JL Kosanovich, SV Gidwani… - Frontiers in …, 2020 - frontiersin.org
Respiratory syncytial virus (RSV) remains the most common cause of lower respiratory tract
infections in children worldwide. Development of a vaccine has been hindered by the risk of …
infections in children worldwide. Development of a vaccine has been hindered by the risk of …
[HTML][HTML] The Japanese encephalitis antigenic complex viruses: from structure to immunity
In the last three decades, several flaviviruses of concern that belong to different antigenic
groups have expanded geographically. This has resulted in the presence of often more than …
groups have expanded geographically. This has resulted in the presence of often more than …