Detailed studies in the past two decades have shown that redox active metals like iron (Fe),
copper (Cu), chromium (Cr), cobalt (Co) and other metals undergo redox cycling reactions …

MTs are small cysteine-rich proteins that chelate metal ions such as Cu+ and Zn2+, and are
widely distributed in several life domains, in particular the eukaryotic one. They are present …

Data about the toxicological interactions of MPs and heavy metals in biota is limited,
particularly in fish early life stages. This study aimed to evaluate the toxicological effects of …

Metallothioneins (MT) are a family of ubiquitous proteins, whose role is still discussed in
numerous papers, but their affinity to some metal ions is undisputable. These cysteine-rich …

Transition metals, such as iron, copper, and zinc, play a very important role in life as the
regulators of various physiochemical reactions in cells. Abnormal distribution and …

The global burden of heavy metal especially mercury, arsenic, lead, and cadmium toxicities
remains a significant public health challenge. Developing nations are particularly at high risk …

Olfaction is orchestrated by olfactory mucosal cells located in the upper nasal cavity.
Olfactory dysfunction manifests early in several neurodegenerative disorders including …

Metallothioneins (MTs) are involved in protection against oxidative stress (OS) and toxic
metals and they participate in zinc metabolism and its homeostasis. Disturbing of zinc …

Human hallmarks of sarcopenia include muscle weakness and a blunted response to
exercise. Nicotinamide N-methyltransferase inhibitors (NNMTis) increase strength and …

Metallothioneins are proteins that are involved in intracellular zinc storage and transport.
Their expression levels have been reported to be elevated in several settings of skeletal …