New insights into the role of mitochondria in cardiac microvascular ischemia/reperfusion injury
As reperfusion therapies have become more widely used in acute myocardial infarction
patients, ischemia-induced myocardial damage has been markedly reduced, but reperfusion …
patients, ischemia-induced myocardial damage has been markedly reduced, but reperfusion …
Role of mitochondrial quality surveillance in myocardial infarction: from bench to bedside
Myocardial infarction (MI) is the irreversible death of cardiomyocyte secondary to prolonged
lack of oxygen or fresh blood supply. Historically considered as merely cardiomyocyte …
lack of oxygen or fresh blood supply. Historically considered as merely cardiomyocyte …
Mitochondrial quality control in cardiac microvascular ischemia-reperfusion injury: new insights into the mechanisms and therapeutic potentials
Thrombolytic therapy and revascularization strategies create a complete recanalization of
the occluded epicardial coronary artery in patients with myocardial infarction (MI). However …
the occluded epicardial coronary artery in patients with myocardial infarction (MI). However …
SERCA overexpression improves mitochondrial quality control and attenuates cardiac microvascular ischemia-reperfusion injury
Despite significant advances in the treatment of myocardial ischemia-reperfusion (I/R) injury,
coronary circulation is a so far neglected target of cardioprotection. In this study, we …
coronary circulation is a so far neglected target of cardioprotection. In this study, we …
Mitochondrial and mitochondrial‐independent pathways of myocardial cell death during ischaemia and reperfusion injury
SM Davidson, A Adameová, L Barile… - Journal of Cellular …, 2020 - Wiley Online Library
Acute myocardial infarction causes lethal injury to cardiomyocytes during both ischaemia
and reperfusion (IR). It is important to define the precise mechanisms by which they die in …
and reperfusion (IR). It is important to define the precise mechanisms by which they die in …
[HTML][HTML] SirT3 activates AMPK-related mitochondrial biogenesis and ameliorates sepsis-induced myocardial injury
T Xin, C Lu - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
Abstract Sirtuin-3 (SirT3) and AMPK stimulate mitochondrial biogenesis, which increases
mitochondrial turnover and cardiomyocyte regeneration. We studied the effects of SirT3 …
mitochondrial turnover and cardiomyocyte regeneration. We studied the effects of SirT3 …
Cardio-oncology-strategies for management of cancer-therapy related cardiovascular disease
Current therapy of advanced cancers is based on several modalities including radiotherapy,
cytotoxic chemotherapy, molecularly targeted inhibitors and antibodies targeting immune …
cytotoxic chemotherapy, molecularly targeted inhibitors and antibodies targeting immune …
Remote ischaemic conditioning: defining critical criteria for success—report from the 11th Hatter Cardiovascular Workshop
Abstract The Hatter Cardiovascular Institute biennial workshop, originally scheduled for April
2020 but postponed for 2 years due to the Covid pandemic, was organised to debate and …
2020 but postponed for 2 years due to the Covid pandemic, was organised to debate and …
Cardioprotective role of melatonin in acute myocardial infarction
Z Fu, Y Jiao, J Wang, Y Zhang, M Shen… - Frontiers in …, 2020 - frontiersin.org
Melatonin is a pleiotropic, indole secreted, and synthesized by the human pineal gland.
Melatonin has biological effects including anti-apoptosis, protecting mitochondria, anti …
Melatonin has biological effects including anti-apoptosis, protecting mitochondria, anti …
Innate immunity as a target for acute cardioprotection
CJ Zuurbier, A Abbate… - Cardiovascular …, 2019 - academic.oup.com
Acute obstruction of a coronary artery causes myocardial ischaemia and if prolonged, may
result in an ST-segment elevation myocardial infarction (STEMI). First-line treatment involves …
result in an ST-segment elevation myocardial infarction (STEMI). First-line treatment involves …