Epilepsy in Down syndrome: a highly prevalent comorbidity

M Altuna, S Giménez, J Fortea - Journal of Clinical Medicine, 2021 - mdpi.com
Individuals with Down syndrome (DS) have an increased risk for epilepsy during the whole
lifespan, but especially after age 40 years. The increase in the number of individuals with DS …

Quality of life in adults with Down syndrome: A mixed methods systematic review

OA Ijezie, J Healy, P Davies, E Balaguer-Ballester… - Plos one, 2023 - journals.plos.org
Background As the life expectancy of adults (aged≥ 18 years) with Down syndrome
increases for a plethora of reasons including recognition of rights, access, and technological …

Machine learning based analysis for intellectual disability in Down syndrome

F Baldo, A Piovesan, M Rakvin, G Ramacieri… - Heliyon, 2023 - cell.com
Down syndrome (DS) or trisomy 21 is the most common genetic cause of intellectual
disability (ID), but a pathogenic mechanism has not been identified yet. Studying a complex …

Executive functioning in preschoolers with 22q11. 2 deletion syndrome and the impact of congenital heart defects

E Everaert, JAS Vorstman, IS Selten, MG Slieker… - Journal of …, 2023 - Springer
Background Executive functioning (EF) is an umbrella term for various cognitive functions
that play a role in monitoring and planning to effectuate goal-directed behavior. The 22q11 …

Co‐occurring conditions in Down syndrome: Findings from a clinical database

NT Baumer, MA Hojlo, KG Pawlowski… - American Journal of …, 2023 - Wiley Online Library
Individuals with Down syndrome (DS) experience a range of medical and
neurodevelopmental conditions, necessitating systematic study of their occurrence and …

Serial assessment of cardiac function and pulmonary hemodynamics in infants with down syndrome

A Smith, N Bussmann, C Breatnach, P Levy… - Journal of the American …, 2022 - Elsevier
Background There is a dearth of longitudinal data describing the evolution of
cardiopulmonary hemodynamics in infants with Down syndrome (DS) beyond infancy. We …

Complexity analysis of the default mode network using resting-state fMRI in down syndrome: relationships highlighted by a neuropsychological assessment

MD Figueroa-Jimenez, M Carbó-Carreté… - Brain Sciences, 2021 - mdpi.com
Background: Studies on complexity indicators in the field of functional connectivity derived
from resting-state fMRI (rs-fMRI) in Down syndrome (DS) samples and their possible …

Trisomy 21 and Congenital Heart Disease: Impact on Health and Functional Outcomes From Birth Through Adolescence: A Scientific Statement From the American …

JK Peterson, S Clarke, BD Gelb… - Journal of the …, 2024 - ahajournals.org
Due to improvements in recognition and management of their multisystem disease, the long‐
term survival of infants, children, and adolescents with trisomy 21 and congenital heart …

The importance of seasonal influenza vaccination for people with disabilities during the COVID-19 pandemic

G Peacock, AB Ryerson, R Koppaka… - Disability and Health …, 2021 - Elsevier
A large proportion of Americans have at least one disability and yet people with disabilities
face inequities in health and health care access. Factors associated with underlying …

Role of adenotonsillectomy and tonsillectomy in children with down syndrome who develop obstructive sleep apnea by obesity as a risk factor

I Ali Khan - International Journal of Pediatrics, 2022 - Wiley Online Library
Down syndrome (DS) or trisomy 21 is caused due to the presence of additional chromosome
21 in humans. DS can exist either as free trisomy 21 (nondisjunction), Robertsonian …