Runs of homozygosity: current knowledge and applications in livestock

E Peripolli, DP Munari, M Silva, ALF Lima… - Animal …, 2017 - Wiley Online Library
This review presents a broader approach to the implementation and study of runs of
homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH …

[HTML][HTML] Understanding crop genetic diversity under modern plant breeding

YB Fu - Theoretical and Applied Genetics, 2015 - Springer
Key message Maximizing crop yield while at the same time minimizing crop failure for
sustainable agriculture requires a better understanding of the impacts of plant breeding on …

Inbreeding and runs of homozygosity: A possible solution to an old problem

I Curik, M Ferenčaković, J Sölkner - Livestock science, 2014 - Elsevier
Quantifying human, plant and livestock inbreeding has been an important goal of
evolutionary biologists and agricultural scientists for nearly a century, and methods to do so …

[HTML][HTML] The distribution of runs of homozygosity and selection signatures in six commercial meat sheep breeds

DC Purfield, S McParland, E Wall, DP Berry - PloS one, 2017 - journals.plos.org
Domestication and the subsequent selection of animals for either economic or
morphological features can leave a variety of imprints on the genome of a population …

[HTML][HTML] Inbreeding and runs of homozygosity before and after genomic selection in North American Holstein cattle

M Forutan, S Ansari Mahyari, C Baes, N Melzer… - BMC genomics, 2018 - Springer
Background While autozygosity as a consequence of selection is well understood, there is
limited information on the ability of different methods to measure true inbreeding. In the …

[HTML][HTML] Invited review: Inbreeding in the genomics era: Inbreeding, inbreeding depression, and management of genomic variability

JT Howard, JE Pryce, C Baes, C Maltecca - Journal of dairy science, 2017 - Elsevier
Traditionally, pedigree-based relationship coefficients have been used to manage the
inbreeding and degree of inbreeding depression that exists within a population. The …

[HTML][HTML] Identification of genomic regions associated with inbreeding depression in Holstein and Jersey dairy cattle

JE Pryce, M Haile-Mariam, ME Goddard… - Genetics Selection …, 2014 - Springer
Background Inbreeding reduces the fitness of individuals by increasing the frequency of
homozygous deleterious recessive alleles. Some insight into the genetic architecture of …

[HTML][HTML] Genetic diversity and signatures of selection in various goat breeds revealed by genome-wide SNP markers

LF Brito, JW Kijas, RV Ventura, M Sargolzaei… - BMC genomics, 2017 - Springer
Background The detection of signatures of selection has the potential to elucidate the
identities of genes and mutations associated with phenotypic traits important for livestock …

[HTML][HTML] Runs of homozygosity and distribution of functional variants in the cattle genome

Q Zhang, B Guldbrandtsen, M Bosse, MS Lund… - BMC genomics, 2015 - Springer
Background Recent developments in sequencing technology have facilitated widespread
investigations of genomic variants, including continuous stretches of homozygous genomic …

Genomic inbreeding estimation in small populations: evaluation of runs of homozygosity in three local dairy cattle breeds

S Mastrangelo, M Tolone, R Di Gerlando, L Fontanesi… - Animal, 2016 - cambridge.org
In the local breeds with small population size, one of the most important problems is the
increase of inbreeding coefficient (F). High levels of inbreeding lead to reduced genetic …