Retinal ganglion cells—diversity of cell types and clinical relevance

US Kim, OA Mahroo, JD Mollon… - Frontiers in neurology, 2021 - frontiersin.org
Retinal ganglion cells (RGCs) are the bridging neurons that connect the retinal input to the
visual processing centres within the central nervous system. There is a remarkable diversity …

Discovery and clinical translation of novel glaucoma biomarkers

G Beykin, AM Norcia, VJ Srinivasan, A Dubra… - Progress in Retinal and …, 2021 - Elsevier
Glaucoma and other optic neuropathies are characterized by progressive dysfunction and
loss of retinal ganglion cells and their axons. Given the high prevalence of glaucoma-related …

Estimating optical coherence tomography structural measurement floors to improve detection of progression in advanced glaucoma

C Bowd, LM Zangwill, RN Weinreb, FA Medeiros… - American journal of …, 2017 - Elsevier
Purpose “Floor effects” in retinal imaging are defined as the points at which no further
structural loss can be detected. We estimated the measurement floors for spectral-domain …

Measurement floors and dynamic ranges of OCT and OCT angiography in glaucoma

S Moghimi, C Bowd, LM Zangwill, RC Penteado… - Ophthalmology, 2019 - Elsevier
Purpose To determine if OCT angiography (OCTA)-derived vessel density measurements
can extend the available dynamic range for detecting glaucoma compared with spectral …

Comparison of glaucoma progression detection by optical coherence tomography and visual field

X Zhang, A Dastiridou, BA Francis, O Tan… - American journal of …, 2017 - Elsevier
Purpose To compare longitudinal glaucoma progression detection using optical coherence
tomography (OCT) and visual field (VF). Design Validity assessment. Methods We analyzed …

Ganglion cell–inner plexiform layer change detected by optical coherence tomography indicates progression in advanced glaucoma

JW Shin, KR Sung, GC Lee, MK Durbin, D Cheng - Ophthalmology, 2017 - Elsevier
Purpose To examine the performance of Guided Progression Analysis (GPA; Carl Zeiss
Meditec, Dublin, CA) in spectral-domain optical coherence tomography (OCT) in detecting …

[HTML][HTML] Residual and dynamic range of retinal nerve fiber layer thickness in glaucoma: comparison of three OCT platforms

JC Mwanza, HY Kim, DL Budenz… - … & visual science, 2015 - tvst.arvojournals.org
Purpose: To estimate visual field (VF) sensitivity at which retinal nerve fiber layer (RNFL)
thinning reaches the measurement floor and at which RNFL stops thinning (change points) …

[HTML][HTML] Structural change can be detected in advanced-glaucoma eyes

A Belghith, FA Medeiros, C Bowd… - … & visual science, 2016 - arvojournals.org
Purpose: To compare spectral-domain optical coherence tomography (SD-OCT) standard
structural measures and a new three-dimensional (3D) volume optic nerve head (ONH) …

Predicting visual field worsening with longitudinal OCT data using a gated transformer network

K Hou, C Bradley, P Herbert, C Johnson, M Wall… - Ophthalmology, 2023 - Elsevier
Purpose To identify visual field (VF) worsening from longitudinal OCT data using a gated
transformer network (GTN) and to examine how GTN performance varies for different …

Clinical factors associated with long-term OCT variability in glaucoma

JH Wu, S Moghimi, E Walker, T Nishida… - American Journal of …, 2023 - Elsevier
PURPOSE To examine clinical factors associated with long-term optical coherence
tomography (OCT)–measured retinal nerve fiber layer thickness (RNFLT) variability in …