Impact of frailty on the effectiveness and safety of non-vitamin K antagonist oral anticoagulants (NOACs) in patients with atrial fibrillation: a nationwide cohort study

M Grymonprez, M Petrovic, TL De Backer… - … Journal-Quality of …, 2024 - academic.oup.com
Aims Data on non-vitamin K antagonist oral anticoagulants (NOACs) use in patients with
atrial fibrillation (AF) and frailty are scarce. Therefore, the impact of frailty on AF-related …

[HTML][HTML] Direct Oral Anticoagulants in Older and Frail Patients with Atrial Fibrillation: A Decade of Experience

JR Spruit, TAC de Vries, MEW Hemels, R Pisters… - Drugs & Aging, 2024 - Springer
Introduction Both the prevalence of atrial fibrillation (AF) and its subsequent use of direct oral
anticoagulants (DOACs) are rapidly increasing in patients of older age. In the absence of …

[HTML][HTML] Diagnosis and Management of Atrial Fibrillation in Acute Ischemic Stroke in the Setting of Reperfusion Therapy: Insights and Strategies for Optimized Care

J Patel, SMM Bhaskar - Journal of Cardiovascular Development and …, 2023 - mdpi.com
Reperfusion therapy in the form of intravenous thrombolysis (IVT) and endovascular
thrombectomy (EVT) has revolutionised the field of stroke medicine. Atrial fibrillation (AF) …

[HTML][HTML] The Effect of Levetiracetam Compared with Enzyme-Inducing Antiseizure Medications on Apixaban and Rivaroxaban Peak Plasma Concentrations

R Goldstein, N Rabkin, N Buchman, AR Jacobs… - CNS drugs, 2024 - Springer
Abstract Background and Objective Post-stroke epilepsy represents an important clinical
challenge as it often requires both treatment with direct oral anticoagulants (DOACs) and …

Effectiveness and safety of direct oral anticoagulation vs. warfarin in frail patients with atrial fibrillation

M Søgaard, AG Ording, F Skjøth… - European Heart …, 2024 - academic.oup.com
Aims Although frail patients with atrial fibrillation (AF) carry a high risk of stroke and
treatment-related bleeding complications, evidence for the safety and effectiveness of …

Impact of premorbid oral anticoagulant use on survival in patients with traumatic intracranial hemorrhage

D Botros, D Gautam, FA Hamrick, S Nguyen… - Neurosurgical …, 2023 - thejns.org
OBJECTIVE Although oral anticoagulant use has been implicated in worse outcomes for
patients with a traumatic brain injury (TBI), prior studies have mostly examined the use of …

Frailty and anticoagulants in older subjects with atrial fibrillation: the EUROSAF study

A Pilotto, N Veronese, MC Polidori… - Age and …, 2023 - academic.oup.com
Aims Literature regarding anticoagulants in older people affected by atrial fibrillation (AF) is
limited to retrospective studies, poorly considering the importance of multidimensional frailty …

Atrial fibrillation management in older hospitalized patients: Evidence of a poor oral anticoagulants prescriptive attitude from the Italian REPOSI registry

V Arcoraci, M Rottura, VM Gianguzzo, G Pallio… - Archives of Gerontology …, 2024 - Elsevier
Atrial fibrillation (AF) prevalence increases in older patients which also show a high
thromboembolic risk. Oral anticoagulants (OACs) are recommended to prevent …

Discontinuation of oral anticoagulant use among nursing home residents with atrial fibrillation before hospice enrollment

Q Chen, J Baek, R Goldberg, J Tjia… - Journal of the …, 2023 - Wiley Online Library
Abstract Background Oral anticoagulants (OACs) are effective in reducing the risk of
cardioembolic stroke due to atrial fibrillation. While most nursing home residents with atrial …

[HTML][HTML] Effectiveness and safety in non-valvular atrial fibrillation patients switching from warfarin to direct oral anticoagulants in US healthcare claims

GYH Lip, V Noxon, A Kang, X Luo, N Atreja… - Journal of Thrombosis …, 2024 - Springer
Introduction There is a paucity of real-world studies examining the risks of stroke/systemic
embolism (SE) and major bleeding (MB) among non-valvular atrial fibrillation (NVAF) …