Bidirectional somatic cell–oocyte signaling is essential to create a changing intrafollicular
microenvironment that controls primordial follicle growth into a cohort of growing follicles …

BACKGROUND Knowledge of the proteomic composition of the gametes is essential to
understand reproductive functions. Most of the sperm proteins are related to …

The ovary is the first organ to age in humans with functional decline evident already in
women in their early 30s. Reproductive aging is characterized by a decrease in oocyte …

Background Follicular fluid is a unique biological fluid in which the critical events of oocyte
and follicular maturation and somatic cell-germ cell communication occur. Because of the …

Human follicular fluid is a complex body fluid that constitutes the microenvironment of
developing follicles in the ovary. Follicular fluid contains a number of proteins that modulate …

Endometriosis, PCOS, and unexplained infertility are currently the most common diseases
rendering large numbers of women infertile worldwide. Oxidative stress, due to its …

A key step in assisted reproduction is the assessment of oocyte and embryo developmental
potential in order to determine the embryo (s) most likely to result in pregnancy. Currently …

Background Human follicular fluid (HFF) provides a key environment for follicle development
and oocyte maturation, and contributes to oocyte quality and in vitro fertilization (IVF) …

Early endometriosis is associated with infertility, and oxidative stress may play a role in the
pathogenesis of disease‐related infertility. This prospective case‐control study aimed to …

Fertility preservation research in women today is increasingly taking advantage of
bioengineering techniques to develop new biomimetic materials and solutions to safeguard …