The skin is the biggest organ of the human being and has many functions. Therefore, the
healing of a skin wound displays an extraordinary mechanism of cascading cellular …

Tissue integrity is maintained by the stroma in physiology. In cancer, however, tissue
invasion is driven by the stroma. Myofibroblasts and cancer‐associated fibroblasts are …

Nueva edición del tratado de referencia en la disciplina que expone los fundamentos de la
anatomía patológica con un formato atractivo y de fácil consulta, que garantiza el acceso a …

As living beings who encounter every kind of traumatic event from paper cut to myocardial
infarction, we must possess ways to heal damaged tissues. While some animals are able to …

Myofibroblasts play a key role in the wound‐healing process, promoting wound closure and
matrix deposition. These cells normally disappear from granulation tissue by apoptosis after …

Significance: Myofibroblasts are responsible for wound closure that occurs in healed acute
wounds. However, their actions can result in disfiguring scar contractures, compromised …

Fibroblasts are the major cell population in the connective tissue of most organs, where they
are essential for their structural integrity. They are best known for their role in remodelling …

Electrical stimulation (ES) has long been used as an alternative clinical treatment and an
effective approach to modulate cellular behaviours. In this work we investigated the effects of …

Hypertrophic scars are unfavorable skin diseases characterized by excessive collagen
deposition. Although systemic treatments exist in clinic to manage hypertrophic scars, they …

Myofibroblasts are central mediators of fibrosis. Typically derived from resident fibroblasts,
myofibroblasts represent a heterogeneous population of cells that are principally defined by …