Zinc coordination complexes as anticancer agents
Zinc, present in all forms of life, is an essential element for humans. It is one of the most
abundant metals in our body. Because of its importance, any malfunctions of its homeostasis …
abundant metals in our body. Because of its importance, any malfunctions of its homeostasis …
[HTML][HTML] Metal complexes of saccharin and thiosaccharin as potential anticancer and antimicrobial agents
Based on the chemotherapeutic success of cisplatin, carboplatin and oxaliplatin as
anticancer drugs, and silver sulfadiazine (AgSDZ) as an antibacterial drug, exploration of the …
anticancer drugs, and silver sulfadiazine (AgSDZ) as an antibacterial drug, exploration of the …
New manganese (II), iron (II), cobalt (II), nickel (II) and copper (II) saccharinate complexes of 2, 6-bis (2-benzimidazolyl) pyridine as potential anticancer agents
New mononuclear complexes [Mn (NO 3)(sac)(H 2 O)(bzimpy)]· 2DMF (Mn),[Fe (sac) 2 (H 2
O)(bzimpy)]· 2H 2 O (Fe),[Co (bzimpy) 2](sac) 2· 2H 2 O (Co),[Ni (bzimpy) 2](sac) 2· H 2 O· i …
O)(bzimpy)]· 2H 2 O (Fe),[Co (bzimpy) 2](sac) 2· 2H 2 O (Co),[Ni (bzimpy) 2](sac) 2· H 2 O· i …
Synthesis, crystal structures, computational studies and α-amylase inhibition of three novel 1, 3, 4-oxadiazole derivatives
Oxadiazoles have broad range of biological applications and have been investigated widely
by the scientific community. In this study, we report the synthesis, X-ray diffraction, density …
by the scientific community. In this study, we report the synthesis, X-ray diffraction, density …
Thiosemicarbazides, 1, 3, 4 thiadiazole Schiff base derivatives of transition metal complexes as antimicrobial agents
M Pervaiz, R Quratulain, A Ejaz, M Shahin… - Inorganic Chemistry …, 2024 - Elsevier
Metal complexes of Schiff base ligands (exhibit imine-C= N-functional group) derived from
thiosemicarbazide and 1, 3, 4 thiadiazole have attracted the attention of researchers on …
thiosemicarbazide and 1, 3, 4 thiadiazole have attracted the attention of researchers on …
Design, synthesis and in vitro anti-proliferative evaluation of new pyridine-2, 3-dihydrothiazole/thiazolidin-4-one hybrids as dual CDK2/GSK3β kinase inhibitors
AF Kassem, AA Sediek, MM Omran, DS Foda… - RSC …, 2024 - pubs.rsc.org
Herein, the molecular hybridization drug discovery approach was used in the design and
synthesis of twelve novel pyridine-2, 3-dihydrothiazole hybrids (2a, b–5a, b and 13a, b–14a …
synthesis of twelve novel pyridine-2, 3-dihydrothiazole hybrids (2a, b–5a, b and 13a, b–14a …
Zn (II), Cd (II) and Hg (II) saccharinate complexes with 2, 6-bis (2-benzimidazolyl) pyridine as promising anticancer agents in breast and lung cancer cell lines via ROS …
New Zn (II), Cd (II) and Hg (II) complexes of saccharinate (sac) and 2, 6-bis (2-
benzimidazolyl) pyridine (bzimpy),[Zn (bzimpy) 2](sac) 2· 2H2O (Zn),[Cd (sac) 2 …
benzimidazolyl) pyridine (bzimpy),[Zn (bzimpy) 2](sac) 2· 2H2O (Zn),[Cd (sac) 2 …
Synthesis, characterization and antileishmanial activity of copper (II) and zinc (II) complexes with diamine ligands
CASR Condé, MV De Almeida, GS Da Silva… - Transition Metal …, 2022 - Springer
A new set of copper-and zinc-diamine (N-alkylated (L1) and N, N'-dialkylated (L2))
complexes,[Cu (L1) 2 (NO3) 2](1),[Cu (L1) 2 (Cl) 2]. 5H2O (2),[Cu (L2) 2 (NO3) 2](3),[Cu (L2) …
complexes,[Cu (L1) 2 (NO3) 2](1),[Cu (L1) 2 (Cl) 2]. 5H2O (2),[Cu (L2) 2 (NO3) 2](3),[Cu (L2) …
Structural characterization, molecular docking assessment, drug-likeness study and DFT investigation of 2-(2-{1, 2-dibromo-2-[3-(4-chloro-phenyl)-[1, 2, 4] oxadiazol-5 …
Abstract The structure of 2-(2-{1, 2 dibromo-2-[3-(4-chloro-phenyl)-[1, 2, 4] oxadiazol-5-yl]-2-
fluoro-ethyl1}-phenyl)-methyl 3-methoxy-acrylic ester (BCOD) was determined using X-ray …
fluoro-ethyl1}-phenyl)-methyl 3-methoxy-acrylic ester (BCOD) was determined using X-ray …
X-ray crystallographic, spectroscopic, and electrochemical properties of Group 12 metal-chlorides of di-2-pyridyl ketone acetic acid hydrazone (dpkaah)
M Bakir, MAW Lawrence, RR Conry - Journal of Coordination …, 2018 - Taylor & Francis
Di-2-pyridyl ketone acetic acid hydrazone hydrate, dpkaah. 0.5 H2O (1), prepared from the
acid catalyzed condensation of di-2-pyridyl ketone (dpk) with acetic acid hydrazide in …
acid catalyzed condensation of di-2-pyridyl ketone (dpk) with acetic acid hydrazide in …