Coping with oxidative stress in reproductive pathophysiology and assisted reproduction: Melatonin as an emerging therapeutical tool

P Cosme, AB Rodríguez, M Garrido, J Espino - Antioxidants, 2022 - mdpi.com
Infertility is an increasing global public health concern with socio-psychological implications
for affected couples. Remarkable advances in reproductive medicine have led to successful …

A review of the use of antioxidants in bovine sperm preparation protocols

V Sapanidou, MP Tsantarliotou… - Animal Reproduction …, 2023 - Elsevier
Reactive oxygen species (ROS) and oxidative stress (OS), the imbalance between the
production of free radicals and the cellular antioxidant defenses, are discussed in relation to …

Use of melatonin in sperm cryopreservation of farm animals: A brief review

J Ofosu, IH Qazi, Y Fang, G Zhou - Animal reproduction science, 2021 - Elsevier
Melatonin (MT) is a potent antioxidant with useful applications in several fields. Due to the
capacity to scavenge free radicals and enhance cellular endogenous antioxidant defenses …

Melatonin improves the motility and DNA integrity of frozen-thawed ram spermatozoa likely via suppression of mitochondrial superoxide production

KR Pool, JP Rickard, SP De Graaf - Domestic Animal Endocrinology, 2021 - Elsevier
The ability of the neurohormone melatonin to ameliorate cryopreservation-induced damage
to spermatozoa has been demonstrated in several domestic species. However, it is unclear …

[HTML][HTML] What is the importance of sperm subpopulations?

F Martínez-Pastor - Animal Reproduction Science, 2022 - Elsevier
The study of sperm subpopulations spans three decades. The origin, meaning, and practical
significance, however, are less clear. Current technology for assessing sperm morphology …

An Overview on Assay Methods to Quantify ROS and Enzymatic Antioxidants in Erythrocytes and Spermatozoa of Small Domestic Ruminants

V Pasciu, M Nieddu, FD Sotgiu, E Baralla, F Berlinguer - Animals, 2023 - mdpi.com
Simple Summary The oxidative stress in the cell is the result of an imbalance between
oxidants and the antioxidant defense system. In particular, oxidative stress in erythrocytes …

NADPH Oxidase 5 and melatonin: Involvement in ram sperm capacitation

S Miguel-Jiménez, B Pina-Beltrán… - Frontiers in Cell and …, 2021 - frontiersin.org
Reactive oxygen species (ROS) play an essential role in mammalian sperm capacitation.
NADPH oxidase 5 (NOX5) has been described as the main source of ROS production in …

Melatonin improves rate of monospermic fertilization and early embryo development in a bovine IVF system

JC Gutiérrez-Añez, H Henning, A Lucas-Hahn… - PloS one, 2021 - journals.plos.org
The developmental competence of male and female gametes is frequently reduced under in
vitro conditions, mainly due to oxidative stress during handling. The amino-acid derived …

Polymorphisms of the melatonin receptor 1A (MTNR1A) gene influence the age at first mating in autumn-born ram-lambs and sexual activity of adult rams in spring

JA Abecia, MC Mura, M Carvajal-Serna, L Pulinas… - Theriogenology, 2020 - Elsevier
The aim of this study was to determine whether polymorphisms of the melatonin receptor 1A
(MTNR1A) gene influence the age at first mating in autumn-born ram-lambs and influence …

Novel methods to detect capacitation-related changes in spermatozoa

NC Bernecic, BM Gadella, T Leahy, SP de Graaf - Theriogenology, 2019 - Elsevier
Prior to interaction with the oocyte, spermatozoa must undergo capacitation, which involves
a series of physio-chemical transformations that occur in the female tract. As capacitation is …