The protective role of estrogen and estrogen receptors in cardiovascular disease and the controversial use of estrogen therapy
Epidemiologic studies have previously suggested that premenopausal females have
reduced incidence of cardiovascular disease (CVD) when compared to age-matched males …
reduced incidence of cardiovascular disease (CVD) when compared to age-matched males …
Mechanistic pathways of sex differences in cardiovascular disease
V Regitz-Zagrosek, G Kararigas - Physiological reviews, 2017 - journals.physiology.org
Major differences between men and women exist in epidemiology, manifestation,
pathophysiology, treatment, and outcome of cardiovascular diseases (CVD), such as …
pathophysiology, treatment, and outcome of cardiovascular diseases (CVD), such as …
The role of matrix metalloproteinase‐9 in atherosclerotic plaque instability
T Li, X Li, Y Feng, G Dong, Y Wang… - Mediators of …, 2020 - Wiley Online Library
Matrix metalloproteinase‐9 (MMP‐9) belongs to the MMP family and has been widely
investigated. Excessive MMP‐9 expression can enhance extracellular matrix degradation …
investigated. Excessive MMP‐9 expression can enhance extracellular matrix degradation …
Cardiovascular effects of exercise training: molecular mechanisms
S Gielen, G Schuler, V Adams - Circulation, 2010 - Am Heart Assoc
In the natural habitat of our ancestors, physical activity was not a preventive intervention but
a matter of survival. In this hostile environment with scarce food and ubiquitous dangers …
a matter of survival. In this hostile environment with scarce food and ubiquitous dangers …
Sex differences in vascular physiology and pathophysiology: estrogen and androgen signaling in health and disease
AC Boese, SC Kim, KJ Yin, JP Lee… - American Journal of …, 2017 - journals.physiology.org
Sex differences between women and men are often overlooked and underappreciated when
studying the cardiovascular system. It has been long assumed that men and women are …
studying the cardiovascular system. It has been long assumed that men and women are …
Concise review: circulating endothelial progenitor cells for vascular medicine
T Asahara, A Kawamoto, H Masuda - Stem cells, 2011 - academic.oup.com
Endothelial progenitor cells (EPCs) have been isolated and shown to be effective in animal
models of ischemia, and many groups involved in clinical trials have demonstrated that EPC …
models of ischemia, and many groups involved in clinical trials have demonstrated that EPC …
[HTML][HTML] Sex, gender, and sex hormones in pulmonary hypertension and right ventricular failure
J Hester, C Ventetuolo, T Lahm - Comprehensive Physiology, 2019 - ncbi.nlm.nih.gov
Pulmonary hypertension (PH) encompasses a syndrome of diseases that are characterized
by elevated pulmonary artery pressure and pulmonary vascular remodeling and that …
by elevated pulmonary artery pressure and pulmonary vascular remodeling and that …
Role of exercise in the prevention of cardiovascular disease: results, mechanisms, and new perspectives
G Schuler, V Adams, Y Goto - European heart journal, 2013 - academic.oup.com
On an empirical basis, exercise has been regarded as a fundamental pre-requisite for
human well-being and physical integrity since classical times. Only in the last decades …
human well-being and physical integrity since classical times. Only in the last decades …
eNOS activation by physical forces: from short-term regulation of contraction to chronic remodeling of cardiovascular tissues
Nitric oxide production in response to flow-dependent shear forces applied on the surface of
endothelial cells is a fundamental mechanism of regulation of vascular tone, peripheral …
endothelial cells is a fundamental mechanism of regulation of vascular tone, peripheral …
Sex-related differences in myocardial remodeling
Sex has a profound impact on myocardial remodeling, which is defined as the molecular
and cellular events after an injury to the myocardium (ie, necrosis, pressure overload …
and cellular events after an injury to the myocardium (ie, necrosis, pressure overload …