Tandem construction of biological relevant aliphatic 5-membered N-heterocycles
D Łowicki, P Przybylski - European Journal of Medicinal Chemistry, 2022 - Elsevier
Nature often uses cascade reactions in a highly stereocontrolled manner for assembly
structurally diverse nitrogen-containing heterocyclic scaffolds, ie secondary metabolites …
structurally diverse nitrogen-containing heterocyclic scaffolds, ie secondary metabolites …
[HTML][HTML] Drug-induced gambling disorder: epidemiology, neurobiology, and management
M Wolfschlag, A Håkansson - Pharmaceutical medicine, 2023 - Springer
Problematic gambling has been suggested to be a possible consequence of dopaminergic
medications used mainly in neurological conditions, ie pramipexole and ropinirole, and …
medications used mainly in neurological conditions, ie pramipexole and ropinirole, and …
[HTML][HTML] Major neurocognitive disorder (dementia)
Objectives: Describe risk factors associated with dementia and related conditions. Review
the evaluation required for patients presenting with cognitive decline. Summarize the …
the evaluation required for patients presenting with cognitive decline. Summarize the …
PARNet: Deep neural network for the diagnosis of parkinson's disease
In this study, the successful network architecture we developed from scratch to diagnose
COVID-19 has been retrained, using single photon emission computed tomography …
COVID-19 has been retrained, using single photon emission computed tomography …
Gene signals and SNPs associated with Parkinson's disease: A nutrigenomics and computational prospective insights
S Subramaniyan, BB Kuriakose, S Mushfiq, NM Prabhu… - Neuroscience, 2023 - Elsevier
Parkinson's disease is the most prevalent chronic neurodegenerative disease. Neurological
conditions for PD were influenced by a variety of epigenetic factors and SNPs in some of the …
conditions for PD were influenced by a variety of epigenetic factors and SNPs in some of the …
[HTML][HTML] Biomarkers in Parkinson's disease: A state of the art review
KY Yamashita, S Bhoopatiraju, BD Silverglate… - Biomarkers in …, 2023 - Elsevier
Biomarkers in Parkinson's disease are widely researched in the field of neuropsychiatry.
Though Parkinson's disease is diagnosed clinically, biomarkers prove to be a promising …
Though Parkinson's disease is diagnosed clinically, biomarkers prove to be a promising …
Practical Overview of 123I-Ioflupane Imaging in Parkinsonian Syndromes
MK Mercer, JW Revels, LC Blacklock, KP Banks… - …, 2024 - pubs.rsna.org
Parkinsonian syndromes are a heterogeneous group of progressive neurodegenerative
disorders involving the nigrostriatal dopaminergic pathway and are characterized by a wide …
disorders involving the nigrostriatal dopaminergic pathway and are characterized by a wide …
[HTML][HTML] Machine learning models for diagnosis and prognosis of Parkinson's disease using brain imaging: general overview, main challenges, and future directions
B Garcia Santa Cruz, A Husch, F Hertel - Frontiers in Aging …, 2023 - frontiersin.org
Parkinson's disease (PD) is a progressive and complex neurodegenerative disorder
associated with age that affects motor and cognitive functions. As there is currently no cure …
associated with age that affects motor and cognitive functions. As there is currently no cure …
Progressive supranuclear palsy: Neuropathology, clinical presentation, diagnostic challenges, management, and emerging therapies
F DeRosier, C Hibbs, K Alessi, I Padda, J Rodriguez… - Disease-a-Month, 2024 - Elsevier
Progressive supranuclear palsy (PSP) is a neurodegenerative disease characterized by the
accumulation of 4R-tau protein aggregates in various brain regions. PSP leads to neuronal …
accumulation of 4R-tau protein aggregates in various brain regions. PSP leads to neuronal …
[HTML][HTML] What is new in nuclear medicine imaging for dementia
Advances in the molecular biology, pathology and genetics of Alzheimer's disease (AD) and
other degenerative dementias have led to the development of biomarkers specific to these …
other degenerative dementias have led to the development of biomarkers specific to these …