The study of botulinum neurotoxins (BoNT) is rapidly progressing in many aspects. Novel
BoNTs are being discovered owing to next generation sequencing, but their biologic and …

Botulinum neurotoxins are diverse proteins. They are currently represented by at least seven
serotypes and more than 40 subtypes. New clostridial strains that produce novel neurotoxin …

Since its introduction as a treatment for strabismus, botulinum toxin (BoNT) has had a
phenomenal journey and is now recommended as first-line treatment for focal dystonia …

Botulinum neurotoxins (BoNTs) and tetanus neurotoxin (TeNT) are the most potent toxins
known and cause botulism and tetanus, respectively. BoNTs are also widely utilized as …

Botulinun neurotoxin (BoNT) has emerged as one of the most multipurpose therapeutic
agents in modern medicine with more clinical applications than any other drug currently on …

Clostridium botulinum, a polyphyletic Gram-positive taxon of bacteria, is classified purely by
their ability to produce botulinum neurotoxin (BoNT). BoNT is the primary virulence factor …

Botulinum neurotoxins (BoNTs), produced by various Clostridium strains, are a family of
potent bacterial toxins and potential bioterrorism agents. Here we report that an …

Tetanus and botulinum neurotoxins cause the neuroparalytic syndromes of tetanus and
botulism, respectively, by delivering inside different types of neurons, metalloproteases …

Botulism is a rare but severe neurological disease in man and animals that is caused by
botulinum neurotoxins (BoNTs) produced by Clostridium botulinum and atypical strains from …

The deadly neurotoxins of Clostridium botulinum (BoNTs) comprise eight serotypes (A–G;
X). The neurotoxin gene cluster encoding BoNT and its accessory proteins includes an …