Traumatic and nontraumatic spinal cord injury: pathological insights from neuroimaging

G David, S Mohammadi, AR Martin… - Nature Reviews …, 2019 - nature.com
Pathophysiological changes in the spinal cord white and grey matter resulting from injury
can be observed with MRI techniques. These techniques provide sensitive markers of …

[HTML][HTML] Challenges for biophysical modeling of microstructure

IO Jelescu, M Palombo, F Bagnato… - Journal of Neuroscience …, 2020 - Elsevier
The biophysical modeling efforts in diffusion MRI have grown considerably over the past 25
years. In this review, we dwell on the various challenges along the journey of bringing a …

[HTML][HTML] SANDI: a compartment-based model for non-invasive apparent soma and neurite imaging by diffusion MRI

M Palombo, A Ianus, M Guerreri, D Nunes… - Neuroimage, 2020 - Elsevier
This work introduces a compartment-based model for apparent cell body (namely soma) and
neurite density imaging (SANDI) using non-invasive diffusion-weighted MRI (DW-MRI). The …

[HTML][HTML] Neurite Exchange Imaging (NEXI): A minimal model of diffusion in gray matter with inter-compartment water exchange

IO Jelescu, A de Skowronski, F Geffroy, M Palombo… - NeuroImage, 2022 - Elsevier
Biophysical models of diffusion in white matter have been center-stage over the past two
decades and are essentially based on what is now commonly referred to as the “Standard …

[HTML][HTML] Diffusion time dependence, power-law scaling, and exchange in gray matter

JL Olesen, L Østergaard, N Shemesh, SN Jespersen - NeuroImage, 2022 - Elsevier
Characterizing neural tissue microstructure is a critical goal for future neuroimaging.
Diffusion MRI (dMRI) provides contrasts that reflect diffusing spins' interactions with myriad …

[HTML][HTML] The sensitivity of diffusion MRI to microstructural properties and experimental factors

M Afzali, T Pieciak, S Newman, E Garyfallidis… - Journal of Neuroscience …, 2021 - Elsevier
Diffusion MRI is a non-invasive technique to study brain microstructure. Differences in the
microstructural properties of tissue, including size and anisotropy, can be represented in the …

Towards unconstrained compartment modeling in white matter using diffusion‐relaxation MRI with tensor‐valued diffusion encoding

B Lampinen, F Szczepankiewicz… - Magnetic resonance …, 2020 - Wiley Online Library
Purpose To optimize diffusion‐relaxation MRI with tensor‐valued diffusion encoding for
precise estimation of compartment‐specific fractions, diffusivities, and T2 values within a two …

[HTML][HTML] Probing brain tissue microstructure with MRI: principles, challenges, and the role of multidimensional diffusion-relaxation encoding

B Lampinen, F Szczepankiewicz, J Lätt, L Knutsson… - NeuroImage, 2023 - Elsevier
Diffusion MRI uses the random displacement of water molecules to sensitize the signal to
brain microstructure and to properties such as the density and shape of cells. Microstructure …

The Dmipy toolbox: diffusion MRI multi-compartment modeling and microstructure recovery made easy

RHJ Fick, D Wassermann, R Deriche - Frontiers in neuroinformatics, 2019 - frontiersin.org
Non-invasive estimation of brain microstructure features using diffusion MRI (dMRI)—known
as Microstructure Imaging—has become an increasingly diverse and complicated field over …

[HTML][HTML] Reproducibility of the standard model of diffusion in white matter on clinical MRI systems

S Coelho, SH Baete, G Lemberskiy, B Ades-Aron… - NeuroImage, 2022 - Elsevier
Estimating intra-and extra-axonal microstructure parameters, such as volume fractions and
diffusivities, has been one of the major efforts in brain microstructure imaging with MRI. The …