Structure and mechanics of integrin-based cell adhesion
MA Arnaout, SL Goodman, JP Xiong - Current opinion in cell biology, 2007 - Elsevier
Integrins are α/β heterodimeric adhesion glycoprotein receptors that regulate a wide variety
of dynamic cellular processes such as cell migration, phagocytosis, and growth and …
of dynamic cellular processes such as cell migration, phagocytosis, and growth and …
[HTML][HTML] AFM for structure and dynamics of biomembranes
EI Goksu, JM Vanegas, CD Blanchette, WC Lin… - … et Biophysica Acta (BBA …, 2009 - Elsevier
We review structure and dynamic measurements of biomembranes by atomic force
microscopy (AFM). We focus mainly on studies involving supported lipid bilayers (SLBs) …
microscopy (AFM). We focus mainly on studies involving supported lipid bilayers (SLBs) …
[HTML][HTML] Atomic force microscopy: a multifaceted tool to study membrane proteins and their interactions with ligands
AM Whited, PSH Park - Biochimica et Biophysica Acta (BBA) …, 2014 - Elsevier
Membrane proteins are embedded in lipid bilayers and facilitate the communication
between the external environment and the interior of the cell. This communication is often …
between the external environment and the interior of the cell. This communication is often …
Three-dimensional multi-scale model of deformable platelets adhesion to vessel wall in blood flow
When a blood vessel ruptures or gets inflamed, the human body responds by rapidly forming
a clot to restrict the loss of blood. Platelets aggregation at the injury site of the blood vessel …
a clot to restrict the loss of blood. Platelets aggregation at the injury site of the blood vessel …
Asymmetric distribution of phosphatidyl serine in supported phospholipid bilayers on titanium dioxide
FF Rossetti, M Textor, I Reviakine - Langmuir, 2006 - ACS Publications
Supported phospholipid bilayers (SPBs) are useful for studying cell adhesion, cell− cell
interactions, protein− lipid interactions, protein crystallization, and applications in biosensor …
interactions, protein− lipid interactions, protein crystallization, and applications in biosensor …
Hemocompatibility comparison of biomedical grade polymers using rabbit thrombogenicity model for preparing nonthrombogenic nitric oxide releasing surfaces
Nitric oxide (NO) is an endogenous vasodilator as well as natural inhibitor of platelet
adhesion/activation. Nitric oxide releasing (NOrel) materials can be prepared by doping an …
adhesion/activation. Nitric oxide releasing (NOrel) materials can be prepared by doping an …
Dissociation of bimolecular αIIbβ3-fibrinogen complex under a constant tensile force
RI Litvinov, V Barsegov, AJ Schissler, AR Fisher… - Biophysical journal, 2011 - cell.com
The regulated ability of integrin αIIbβ3 to bind fibrinogen plays a crucial role in platelet
aggregation, adhesion, and hemostasis. Employing an optical-trap-based electronic force …
aggregation, adhesion, and hemostasis. Employing an optical-trap-based electronic force …
Atomic force microscopy studies of the initial interactions between fibrinogen and surfaces
LC Xu, CA Siedlecki - Langmuir, 2009 - ACS Publications
Atomic force microscopy (AFM) was used to analyze the interactions between fibrinogen and
model surfaces having different levels of water wettability. In contrast to most AFM studies …
model surfaces having different levels of water wettability. In contrast to most AFM studies …
Experimental techniques to study protein dynamics and conformations
Proteins are flexible biomolecules and can adopt a wide range of structural conformations
such that they can have their whole conformational ensemble. Understanding of protein …
such that they can have their whole conformational ensemble. Understanding of protein …
Microfluidic chip grafted with integrin tension sensors for evaluating the effects of flowing shear stress and ROCK inhibitor on platelets
Integrins are key players in platelet adhesion and aggregation. Integrin molecular tensions,
the forces transmitted by integrin molecules, are regulated by both mechanical and …
the forces transmitted by integrin molecules, are regulated by both mechanical and …