Proteomic alteration in the progression of multiple myeloma: A comprehensive review

NH Ismail, A Mussa, MJ Al-Khreisat, S Mohamed Yusoff… - Diagnostics, 2023 - mdpi.com
Multiple myeloma (MM) is an incurable hematologic malignancy. Most MM patients are
diagnosed at a late stage because the early symptoms of the disease can be uncertain and …

Role of NF-κB signaling in the interplay between multiple myeloma and mesenchymal stromal cells

M Cippitelli, H Stabile, A Kosta, S Petillo… - International Journal of …, 2023 - mdpi.com
Nuclear factor-κB (NF-κB) transcription factors play a key role in the pathogenesis of multiple
myeloma (MM). The survival, proliferation and chemoresistance of malignant plasma cells …

[HTML][HTML] Dysregulation of Non-Coding RNAs: Roles of miRNAs and lncRNAs in the Pathogenesis of Multiple Myeloma

NH Ismail, A Mussa, MJ Al-Khreisat… - Non-coding RNA, 2023 - mdpi.com
The dysregulation of non-coding RNAs (ncRNAs), specifically microRNAs (miRNAs) and
long non-coding RNAs (lncRNAs), leads to the development and advancement of multiple …

Targeted therapy for multiple myeloma: an overview on CD138-based strategies

F Riccardi, C Tangredi, M Dal Bo, G Toffoli - Frontiers in Oncology, 2024 - frontiersin.org
Multiple myeloma (MM) is an incurable hematological disease characterized by the
uncontrolledgrowth of plasma cells primarily in the bone marrow. Although its treatment …

Increased Expression of SRSF1 Predicts Poor Prognosis in Multiple Myeloma

J Zhang, Z Wang, K Wang, D Xin, L Wang… - Journal of …, 2023 - Wiley Online Library
Background. Multiple myeloma (MM) is a clonal plasma cell disorder which still lacks
sufficient prognostic factors. The serine/arginine‐rich splicing factor (SRSF) family serves as …

Multiple myeloma: signaling pathways and targeted therapy

Q Lu, D Yang, H Li, T Niu, A Tong - Molecular Biomedicine, 2024 - Springer
Multiple myeloma (MM) is the second most common hematological malignancy of plasma
cells, characterized by osteolytic bone lesions, anemia, hypercalcemia, renal failure, and the …

Synergistic effect of docetaxel combined with a novel multi-target inhibitor CUDC-101 on inhibiting human prostate cancer

Z Li, C Quan, W Li, M Ji - Pathology-Research and Practice, 2023 - Elsevier
Histone deacetylases (HDACs) are commonly overexpressed in several types of human
cancers, including prostate cancer (PCa). Histone deacetylase inhibitors (HDACis) are …

Lysin (K)-specific demethylase 1 inhibition enhances proteasome inhibitor response and overcomes drug resistance in multiple myeloma

C Bandini, E Mereu, T Paradzik, M Labrador… - … Hematology & Oncology, 2023 - Springer
Background Multiple myeloma (MM) is an incurable plasma cell malignancy, accounting for
approximately 1% of all cancers. Despite recent advances in the treatment of MM, due to the …