Cancer is the second leading cause of human death across the world. Tripartite motif (TRIM)
family, with E3 ubiquitin ligase activities in majority of its members, is reported to be involved …

Tripartite motif (TRIM) 31 is a new member of the TRIM family and functions as an E3
ubiquitin ligase. Abnormal TRIM31 expression leads to a variety of pathological conditions …

Aim Perioperative neurocognitive disorders (PND) occur frequently after surgery and
anesthesia, especially in aged patients. Previous studies have shown multiple PND related …

Ubiquitination is a post-translational modification that has pivotal roles in protein
degradation and diversified cellular processes, and for more than two decades it has been a …

The ubiquitylation machinery regulates several fundamental biological processes from
protein homeostasis to a wide variety of cellular signaling pathways. As a consequence, its …

Colorectal cancer (CRC) represents one of the most widespread forms of cancer in the
population and, as all malignant tumors, often develops resistance to chemotherapies with …

Abstract Tripartite motif 8 (TRIM8) is an E3 ligase that plays dual roles in various tumor
types. The biological effects and underlying mechanism of TRIM8 in hepatocellular …

Background and aim Allergic asthma is a primary type of asthma and characterized by T
helper 2 (Th2) cells-mediated inflammation. Tripartite motif containing 8 (TRIM8) protein is …

Simple Summary The tripartite motif (TRIM) gene family is a large group of E3 ubiquitin
ligase proteins that can also have proteasome-independent functions. This review …

Acute lung injury (ALI) is an inflammatory disorder of the lung that causes high mortality and
lacks any pharmacological intervention. Ubiquitination plays a critical role in the …