Pancreatic beta cell death: novel potential mechanisms in diabetes therapy

J Rojas, V Bermudez, J Palmar… - Journal of Diabetes …, 2018 - Wiley Online Library
Purpose of Review. Describing the diverse molecular mechanisms (particularly
immunological) involved in the death of the pancreatic beta cell in type 1 and type 2 …

Conservation of adaptive potential and functional diversity: integrating old and new approaches

BK Mable - Conservation Genetics, 2019 - Springer
Continuing advances in whole genome scale approaches integrated with other
'omic'technologies promise to revolutionise understanding about the relevance of genetic …

Genetic mixing for population management: From genetic rescue to provenancing

AA Hoffmann, AD Miller, AR Weeks - Evolutionary Applications, 2021 - Wiley Online Library
Animal and plant species around the world are being challenged by the deleterious effects
of inbreeding, loss of genetic diversity, and maladaptation due to widespread habitat …

Cancer in wildlife: patterns of emergence

PA Pesavento, D Agnew, MK Keel… - Nature Reviews Cancer, 2018 - nature.com
Cancer is ubiquitous in wildlife, affecting animals from bivalves to pachyderms and
cetaceans. Reports of increasing frequency demonstrate that neoplasia is associated with …

Conservation genomics of threatened animal species

CC Steiner, AS Putnam, PEA Hoeck… - Annu. Rev. Anim …, 2013 - annualreviews.org
The genomics era has opened up exciting possibilities in the field of conservation biology by
enabling genomic analyses of threatened species that previously were limited to model …

The role of major histocompatibility complex in organ transplantation-donor specific anti-major histocompatibility complex antibodies analysis goes to the next stage

T Nakamura, T Shirouzu, K Nakata… - International journal of …, 2019 - mdpi.com
Organ transplantation has progressed with the comprehension of the major
histocompatibility complex (MHC). It is true that the outcome of organ transplantation largely …

Black and white and read all over: the past, present and future of giant panda genetics

F Wei, Y Hu, L Zhu, MW Bruford, X Zhan… - Molecular …, 2012 - Wiley Online Library
Few species attract much more attention from the public and scientists than the giant panda
(A iluropoda melanoleuca), a popular, enigmatic but highly endangered species. The …

Avian MHC evolution in the era of genomics: phase 1.0

EA O'Connor, H Westerdahl, R Burri, SV Edwards - Cells, 2019 - mdpi.com
Birds are a wonderfully diverse and accessible clade with an exceptional range of ecologies
and behaviors, making the study of the avian major histocompatibility complex (MHC) of …

The effect of body size and inbreeding on cancer mortality in breeds of the domestic dog: a test of the multi-stage model of carcinogenesis

L Nunney - Royal Society Open Science, 2024 - royalsocietypublishing.org
Cancer is a leading cause of death in domestic dogs. Deaths due to cancer vary widely
among breeds, providing an opportunity for testing the multi-stage model of carcinogenesis …

The evolutionary ecology of transmissible cancers

B Ujvari, RA Gatenby, F Thomas - Infection, Genetics and Evolution, 2016 - Elsevier
Transmissible tumours, while rare, present a fascinating opportunity to examine the
evolutionary dynamics of cancer as both an infectious agent and an exotic, invasive species …