A renewed concept on the MAPK signaling pathway in cancers: Polyphenols as a choice of therapeutics

J Anjum, S Mitra, R Das, R Alam, A Mojumder… - Pharmacological …, 2022 - Elsevier
Abnormalities in the mitogen-activated protein kinase (MAPK) signaling pathway are a key
contributor to the carcinogenesis process and have therefore been implicated in several …

Fisetin and quercetin: promising flavonoids with chemopreventive potential

D Kashyap, VK Garg, HS Tuli, MB Yerer, K Sak… - Biomolecules, 2019 - mdpi.com
Despite advancements in healthcare facilities for diagnosis and treatment, cancer remains
the leading cause of death worldwide. As prevention is always better than cure, efficient …

Fisetin: a dietary antioxidant for health promotion

N Khan, DN Syed, N Ahmad… - Antioxidants & redox …, 2013 - liebertpub.com
Significance: Diet-derived antioxidants are now being increasingly investigated for their
health-promoting effects, including their role in the chemoprevention of cancer. In general …

Evidence of flavonoids on disease prevention

M Li, M Qian, Q Jiang, B Tan, Y Yin, X Han - Antioxidants, 2023 - mdpi.com
A growing body of evidence highlights the properties of flavonoids in natural foods for
disease prevention. Due to their antioxidative, anti-inflammatory, and anti-carcinogenic …

Immunomodulatory effects of flavonoids: possible induction of T CD4+ regulatory cells through suppression of mTOR pathway signaling activity

A Hosseinzade, O Sadeghi… - Frontiers in …, 2019 - frontiersin.org
The increasing rate of autoimmune disorders and cancer in recent years has been a
controversial issue in all aspects of prevention, diagnosis, prognosis and treatment. Among …

Fisetin: An anticancer perspective

M Imran, F Saeed, SA Gilani, MA Shariati… - Food science & …, 2021 - Wiley Online Library
Despite the provision of safe and cost‐effective chemopreventive cancer approaches, still
there are requirements to enhance their efficiency. The use of dietary agents as …

Autophagy and cancer

KS Choi - Experimental & molecular medicine, 2012 - nature.com
Basal autophagy plays a critical role in maintaining cellular homeostasis and genomic
integrity by degrading aged or malfunctioning organelles and damaged or misfolded …

Salt-tolerant plants, halophytes, as renewable natural resources for cancer prevention and treatment: roles of phenolics and flavonoids in immunomodulation and …

HA Mohammed, AH Emwas, RA Khan - International Journal of Molecular …, 2023 - mdpi.com
Halophytes and xerophytes, plants with adequate tolerance to high salinity with strong ability
to survive in drought ecosystem, have been recognized for their nutritional and medicinal …

Fisetin, a potent anticancer flavonol exhibiting cytotoxic activity against neoplastic malignant cells and cancerous conditions: A scoping, comprehensive review

R Kubina, K Krzykawski, A Kabała-Dzik, RD Wojtyczka… - Nutrients, 2022 - mdpi.com
Diet plays a crucial role in homeostasis maintenance. Plants and spices containing
flavonoids have been widely used in traditional medicine for thousands of years. Flavonols …

Dietary polyphenols in prevention and treatment of prostate cancer

RK Lall, DN Syed, VM Adhami, MI Khan… - International journal of …, 2015 - mdpi.com
Prostate cancer is the most prevalent disease affecting males in many Western countries,
with an estimated 29,480 deaths in 2014 in the US alone. Incidence rates for prostate cancer …