Colorectal cancer is considered one of the major malignancies that threaten the lives and
health of people around the world. Patients with CRC are prone to post-operative local …

There is increasing interest in the use of natural compounds with beneficial pharmacological
effects for managing diseases. Curcumin (CUR) is a phytochemical that is reportedly …

Functional studies on colorectal cancer cells indicated a protective role of the interferon‐
inducible dsDNA sensor Absent in Melanoma 2 (AIM2) in cancer progression. Given that a …

Purpose Tumour budding is defined as the presence of isolated or small clusters of
malignant cells at the invasive edge of the tumour. It is considered a negative prognostic …

Tumors continually shed DNA into the circulation, where it can be noninvasively accessed.
The ability to accurately detect circulating tumor DNA (ctDNA) could significantly impact the …

The NCCN Clinical Practice Guidelines in Oncology for Colon Cancer begin with the clinical
presentation of the patient to the primary care physician or gastroenterologist and address …

Background The aim of the trial was to compare two active adjuvant chemotherapy regimens
in patients with early stage colorectal cancer (CRC). Methods Patients were assigned to …

The majority of patients with prostate cancer who later develop lethal metastatic disease
have high-risk localized disease at presentation, emphasizing the importance of effective …

In 2013, the American Cancer Society estimated that 102,480 people would be diagnosed
with colon cancer, 1 and approximately one-third of these would be diagnosed with stage II …

The prognostic value of lymphovascular invasion (LVI) in stage I/II colorectal cancer (CRC)
does not reach a consensus. To systematically assess prognostic significance of LVI …