Autophagy protects against aminochrome-induced cell death in substantia nigra-derived cell line

I Paris, P Munoz, S Huenchuguala… - Toxicological …, 2011 - academic.oup.com
Aminochrome, the precursor of neuromelanin, has been proposed to be involved in the
neurodegeneration neuromelanin-containing dopaminergic neurons in Parkinson's disease …

Resolution of neutrophilic inflammation by H2O2 in antigen‐induced arthritis

F Lopes, FM Coelho, VV Costa, ÉLM Vieira… - Arthritis & …, 2011 - Wiley Online Library
Objective Neutrophil accumulation contributes to the pathogenesis of rheumatoid arthritis.
This study was undertaken to examine the ability of H2O2 to influence neutrophilic …

Avermectin exposure induces apoptosis in King pigeon brain neurons

S Li, M Li, Y Cui, X Wang - Pesticide biochemistry and physiology, 2013 - Elsevier
The effect of avermectin was studied on King pigeon brain nerve cells by cytotoxicity [3-(4, 5-
dimethylthiazol-2-yl)-2, 5-diphenyl-tetrazolium bromide, MTT] and apoptosis [acridine …

Ultrastructural characterization of rat neurons in primary culture

F Robert, JF Cloix, T Hevor - Neuroscience, 2012 - Elsevier
Few studies have addressed the ultrastructure and morphology of neurons in primary pure
culture. We therefore use immunohistochemistry and electron microscopy to investigate the …

Hydrogen peroxide mediated the neurotoxicity of an antibody against plasmalemmal neuronspecific enolase in primary cortical neurons

Y Yamamoto, H Koma, T Yagami - Neurotoxicology, 2015 - Elsevier
Neuron-specific enolase (NSE) is not only a glycolytic enzyme in the cytosol, but also
localized in the synaptic plasma membrane. The plasmalemmal NSE is one of autoantigen …

Ligand-dependent corepressor contributes to transcriptional repression by C2H2 zinc-finger transcription factor ZBRK1 through association with KRAB-associated …

MR Calderon, M Verway, RO Benslama… - Nucleic acids …, 2014 - academic.oup.com
We identified a novel interaction between ligand-dependent corepressor (LCoR) and the
corepressor KRAB-associated protein-1 (KAP-1). The two form a complex with C2H2 zinc …

L-type voltage-dependent calcium channel is involved in the snake venom group IA secretory phospholipase A2-induced neuronal apoptosis

T Yagami, Y Yamamoto, H Kohma, T Nakamura… - Neurotoxicology, 2013 - Elsevier
Snake venom group IA secretory phospholipase A2 (sPLA2-IA) is known as a neurotoxin.
Snake venom sPLA2s are neurotoxic in vivo and in vitro, causing synergistic neurotoxicity to …

Lymphatic cells do not functionally integrate into 3D organotypic brain slice cultures, but aggregate around penetrating blood vessels

CH Lam, C Janson, L Romanova… - Experimental Brain …, 2022 - Springer
Brain slice culture (BSC) is a well-known three-dimensional model of the brain. In this study,
we use organotypic slices for studying neuro-lymphatic physiology, to directly test the …

Leukotriene receptor antagonists, LY293111 and ONO-1078, protect neurons from the sPLA2-IB-induced neuronal cell death independently of blocking their receptors

T Yagami, Y Yamamoto, H Kohma - Neurochemistry International, 2013 - Elsevier
In the ischemic brain, leukotrienes (LTs) are increased and their receptor antagonists protect
neurons. However, it has not yet been sufficiently clarified how antagonists for LT receptors …

[PDF][PDF] FGF-2 在细胞凋亡中的作用机制

潘运迎, 邓征浩, 周建华 - 现代生物医学进展, 2012 - biomed.cnjournals.com
成纤维细胞生长因子2 (fibroblast growth factor 2, FGF-2) 具有多种细胞生物学功能. FGF-2
在肿瘤组织中呈高水平表达状态, 且可抑制多种化疗药物的促凋亡作用, 从而曾为肿瘤细胞存活 …