Extracellular vesicles as new players in drug delivery: a focus on red blood cells-derived EVs

S Biagiotti, F Abbas, M Montanari, C Barattini, L Rossi… - Pharmaceutics, 2023 - mdpi.com
The article is divided into several sections, focusing on extracellular vesicles'(EVs) nature,
features, commonly employed methodologies and strategies for their isolation/preparation …

Circulating tumor cells with metastasis-initiating competence survive fluid shear stress during hematogenous dissemination through CXCR4-PI3K/AKT signaling

Y Xin, B Hu, K Li, G Hu, C Zhang, X Chen, K Tang… - Cancer Letters, 2024 - Elsevier
To seed lethal secondary lesions, circulating tumor cells (CTCs) must survive all rate-limiting
factors during hematogenous dissemination, including fluid shear stress (FSS) that poses a …

Efficient and highly reproducible production of red blood cell-derived extracellular vesicle mimetics for the loading and delivery of RNA molecules

S Biagiotti, B Canonico, M Tiboni, F Abbas, E Perla… - Scientific Reports, 2024 - nature.com
Extracellular vesicles (EVs) are promising natural nanocarriers for the delivery of therapeutic
agents. As with any other kind of cell, red blood cells (RBCs) produce a limited number of …

Aberrant GPA expression and regulatory function of red blood cells in sickle cell disease

JN Marshall, MN Klein, P Karki, K Promnares… - Blood …, 2024 - ashpublications.org
Glycophorin A (GPA), a red blood cell (RBC) surface glycoprotein, can maintain peripheral
blood leukocyte quiescence through interaction with a sialic acid–binding Ig-like lectin …