Dysfunctional mitochondria as critical players in the inflammation of autoimmune diseases: Potential role in Sjögren's syndrome

MJ Barrera, S Aguilera, I Castro, P Carvajal, D Jara… - Autoimmunity …, 2021 - Elsevier
Relevant reviews highlight the association between dysfunctional mitochondria and
inflammation, but few studies address the contribution of mitochondria and mitochondria …

Mitochondrial dynamics, mitophagy, and mitochondria–endoplasmic reticulum contact sites crosstalk under hypoxia

S Wang, J Tan, Y Miao, Q Zhang - Frontiers in cell and developmental …, 2022 - frontiersin.org
Mitochondria are double membrane organelles within eukaryotic cells, which act as cellular
power houses, depending on the continuous availability of oxygen. Nevertheless, under …

The ELK3-DRP1 axis determines the chemosensitivity of triple-negative breast cancer cells to CDDP by regulating mitochondrial dynamics

JD Park, HJ Jang, SH Choi, GH Jo, JH Choi… - Cell death …, 2023 - nature.com
Triple-negative breast cancer (TNBC) is the most lethal form of breast cancer. TNBC patients
have higher rates of metastasis and restricted therapy options. Although chemotherapy is …

Mitochondrial miR-12294-5p regulated copper-induced mitochondrial oxidative stress and mitochondrial quality control imbalance by targeted inhibition of CISD1 in …

G Zhong, Y Li, L Li, Y Huo, W Zhang, T Li, F Ma… - Journal of Hazardous …, 2023 - Elsevier
Copper (Cu) is hazardous metal contaminant, which induced hepatotoxicity is closely
related to mitochondrial disorder, but exact regulatory mechanism has not yet been …

[HTML][HTML] Chronic arsenic exposure-provoked biotoxicity involved in liver-microbiota-gut axis disruption in chickens based on multi-omics technologies

J Li, C Guo, Y Liu, B Han, Z Lv, H Jiang, S Li… - Journal of Advanced …, 2024 - Elsevier
Introduction Arsenic has been ranked as the most hazardous substance by the US Agency
for Toxic Substances and Disease Registry. Environmental arsenic exposure-evoked health …

Miquelianin, a main functional flavonoid of lotus leaf, induces thermogenic signature via p38‐PINK1‐PARKIN‐mediated mitophagy and mimicking NRF2 signaling …

Z Wang, C Xue, T Yang, M Zeng, Z Wang… - Food …, 2023 - Wiley Online Library
Adipocytes thermogenesis is an important mechanism for increasing energy expenditure.
Here, screening of thermogenic activators (Sirt1 and Ucp1) investigated in C3H10T1/2 cells …

Mitochondria have made a long evolutionary path from ancient bacteria immigrants within eukaryotic cells to essential cellular hosts and key players in human health …

A Atlante, D Valenti - Current Issues in Molecular Biology, 2023 - mdpi.com
Mitochondria have made a long evolutionary path from ancient bacteria immigrants within
the eukaryotic cell to become key players for the cell, assuming crucial multitasking skills …

[HTML][HTML] Targeting the multifaceted roles of mitochondria in intracerebral hemorrhage and therapeutic prospects

Y Li, H Liu, C Tian, N An, K Song, Y Wei, Y Sun… - Biomedicine & …, 2022 - Elsevier
Intracerebral hemorrhage (ICH) is a severe, life-threatening subtype of stoke that constitutes
a crucial health and socioeconomic problem worldwide. However, the current clinical …

Mitochondrial dysfunction and mitochondrion-targeted therapeutics in liver diseases

L Xiang, Y Shao, Y Chen - Journal of Drug Targeting, 2021 - Taylor & Francis
The liver is a vital metabolic and detoxifying organ and suffers diverse endogenous or
exogenous damage. Hepatocyte mitochondria experience various structural and functional …

A pivotal role of selective autophagy in mitochondrial quality control: implications for zinc oxide nanoparticles induced neurotoxicity

L Wang, Z Duan, M Liang, C Wang, T Liang… - Chemico-Biological …, 2022 - Elsevier
Excessive occupational, medical, and environmental exposure of zinc oxide nanoparticles
(ZnONPs) caused its accumulation in the nervous system and raised global concerns over …