Purpose Cisplatin-based combination chemotherapy is considered standard first-line
treatment for patients with metastatic urothelial carcinoma. However, a large proportion of …

Although radiotherapy improves locoregional control and survival in patients with non-small-
cell lung cancer, radiation pneumonitis is a common treatment-related toxicity. Many …

Background It is unknown whether combined chemoradiotherapy improves overall survival
in elderly patients with locally advanced non-small-cell lung cancer (NSCLC). The aim of …

Purpose To derive recommendations for routine practice and clinical trials for techniques
used in high-dose, high-precision thoracic radiotherapy for lung cancer. Methods A literature …

Background Despite several randomised trials comparing radiotherapy alone with
concomitant radio-chemotherapy in patients with locally advanced non-small cell lung …

Abstract Learning Objectives After completing this course, the reader will be able to: Discuss
the implications of age bias in clinical trials. Describe the effects of applying clinical trial …

Purpose Because comorbidity affects cancer treatment outcomes, guidelines recommend
considering comorbidity when making treatment decisions in older patients with lung cancer …

Purpose: To determine the clinical, dosimetric, and spatial parameters that correlate with
radiation pneumonitis. Methods and Materials: Patients treated with high-dose radiation for …

The decision to administer a radical course of radiotherapy (RT) is largely influenced by the
dose-volume metrics of the treatment plan, but what are the patient-related and other factors …

Background Comorbidities and risk factors likely to complicate treatment are common in
elderly cancer patients. Anthracyclines remain the cornerstone of first-line therapy for non …