[HTML][HTML] History and perspective of immunotherapy for pythiosis
H Yolanda, T Krajaejun - Vaccines, 2021 - mdpi.com
The fungus-like microorganism Pythium insidiosum causes pythiosis, a life-threatening
infectious disease increasingly reported worldwide. Antimicrobial drugs are ineffective …
infectious disease increasingly reported worldwide. Antimicrobial drugs are ineffective …
[HTML][HTML] The molecular dialog between oomycete effectors and their plant and animal hosts
M Saraiva, ME Ściślak, YT Ascurra, TM Ferrando… - Fungal Biology …, 2023 - Elsevier
Oomycetes form a phylogenetically distinct group of eukaryotic microorganisms that include
some of the most notorious pathogens of plants and animals. Through the deployment of a …
some of the most notorious pathogens of plants and animals. Through the deployment of a …
A PAX6-regulated receptor tyrosine kinase pairs with a pseudokinase to activate immune defense upon oomycete recognition in Caenorhabditis elegans
F Drury, M Grover, M Hintze… - Proceedings of the …, 2023 - National Acad Sciences
Oomycetes were recently discovered as natural pathogens of Caenorhabditis elegans, and
pathogen recognition alone was shown to be sufficient to activate a protective transcriptional …
pathogen recognition alone was shown to be sufficient to activate a protective transcriptional …
[HTML][HTML] Neutrophil extracellular traps and phagocytosis in Pythium insidiosum
A Sriwarom, D Chiewchengchol, S Saithong… - Plos one, 2023 - journals.plos.org
Neutrophils are innate immune cells that play crucial roles in response to extracellular
pathogens, including bacteria and fungi. Pythium insidiosum (P insidiosum) is a fungus-like …
pathogens, including bacteria and fungi. Pythium insidiosum (P insidiosum) is a fungus-like …
Elevated Levels of Interleukins, Leukocyte Protein and Cathelicidin Antimicrobial Peptide are Strongly Associated with Early to Mid-Stage of Pythium insidiosum …
LK Ahirwar, S Sharma - Current Eye Research, 2022 - Taylor & Francis
Purpose Corneal infection in humans caused by Pythium insidiosum can lead to blindness
and the host ocular immune response to it is less studied. Herein, we investigate the …
and the host ocular immune response to it is less studied. Herein, we investigate the …
Defective cytokine production from monocytes/macrophages of E-beta thalassemia patients in response to Pythium insidiosum infection
S Ud-Naen, T Tansit, D Kanistanon, A Chaiprasert… - Immunobiology, 2019 - Elsevier
Background Pythium insidiosum has been mainly reported to cause morbidity and mortality
in thalassemia patients. P. insidiosum zoospores can germinate to be hyphae within a few …
in thalassemia patients. P. insidiosum zoospores can germinate to be hyphae within a few …
In vivo effect of minocycline alone and in combination with immunotherapy against pythium insidiosum
CEP Zimmermann, FPK Jesus, KB Schlemmer… - Veterinary …, 2020 - Elsevier
This study examined the effect of minocycline alone and in combination with immunotherapy
against pythiosis. Twenty rabbits, aged three months old and subcutaneously inoculated …
against pythiosis. Twenty rabbits, aged three months old and subcutaneously inoculated …
Immunotherapy based on Pythium insidiosum mycelia drives a Th1/Th17 response in mice
JSM Tondolo, ES Loreto, FPK de Jesus… - Medical …, 2020 - academic.oup.com
Pythium insidiosum is an oomycete that affects mammals, especially humans and horses,
causing a difficult-to-treat disease. Typically, surgical interventions associated with …
causing a difficult-to-treat disease. Typically, surgical interventions associated with …
Pythium insidiosum–An Emerging Mammalian Pathogen
ES Loreto, JSM Tondolo, JM Santurio - Pythium, 2020 - taylorfrancis.com
Pythiosis is an aggressive and life-threating infection caused by the oomycete Pythium
insidiosum. The disease occurs mainly in tropical and subtropical countries and affects …
insidiosum. The disease occurs mainly in tropical and subtropical countries and affects …
A receptor tyrosine kinase regulated by the transcription factor VAB-3/PAX6 pairs with a pseudokinase to trigger immune signalling upon oomycete recognition in C …
F Drury, M Grover, M Hintze, J Saunders, MK Fasseas… - bioRxiv, 2022 - biorxiv.org
Oomycetes were recently discovered as natural pathogens of Caenorhabditis elegans and
pathogen recognition alone was shown to be sufficient to activate a protective transcriptional …
pathogen recognition alone was shown to be sufficient to activate a protective transcriptional …