Functional nucleic acids (FNAs), including DNA aptamers and DNAzymes, are finding
increasing use as molecular recognition elements for point-of-care (POC) assays and …

Rapid detection of nucleic acids (DNA or RNA) by inexpensive, selective, accurate, and
highly sensitive methods is very important for biosensors. DNA-sensors based on DNA …

Genome editing technologies based on DNA-dependent polymerases (DDPs) could offer
several benefits compared with other types of editors to install diverse edits. Here, we …

DNA methylation is the most common form of DNA modification in prokaryotic and eukaryotic
genomes. We have applied the method of single-molecule, real-time (SMRT®) DNA …

Coupling nucleic acid processing enzymes to nanoscale pores allows controlled movement
of individual DNA or RNA strands that is reported as an ionic current/time series. Hundreds …

Binuclear metallohydrolases are a structurally diverse group of enzymes that use binuclear
metal ion centers to catalyze the hydrolysis of amides and esters of carboxylic and …

Pacific Biosciences has developed a method for real-time sequencing of single DNA
molecules (Eid et al., 2009), with intrinsic sequencing rates of several bases per second and …

Adenoviruses represent ubiquitous and clinically significant human pathogens, gene‐
delivery vectors, and oncolytic agents. The study of adenovirus‐infected cells has long been …

Techniques for the single-step amplification of whole genomes have been developed into
powerful tools for phylogenetic analyses, epidemiological studies and studies on genome …

Adenoviruses have attracted much attention as probes to study biological processes such as
DNA replication, transcription, splicing, and cellular transformation. More recently these …