Genetic causes and modifiers of autism spectrum disorder

L Rylaarsdam, A Guemez-Gamboa - Frontiers in cellular …, 2019 - frontiersin.org
Autism Spectrum Disorder (ASD) is one of the most prevalent neurodevelopmental
disorders, affecting an estimated 1 in 59 children. ASD is highly genetically heterogeneous …

Autism spectrum disorders and the gut microbiota

A Fattorusso, L Di Genova, GB Dell'Isola, E Mencaroni… - Nutrients, 2019 - mdpi.com
In recent years, there has been an emerging interest in the possible role of the gut
microbiota as a co-factor in the development of autism spectrum disorders (ASDs), as many …

The neuropharmacology of butyrate: the bread and butter of the microbiota-gut-brain axis?

RM Stilling, M Van De Wouw, G Clarke… - Neurochemistry …, 2016 - Elsevier
Several lines of evidence suggest that brain function and behaviour are influenced by
microbial metabolites. Key products of the microbiota are short-chain fatty acids (SCFAs) …

Autism spectrum disorder: neuropathology and animal models

M Varghese, N Keshav, S Jacot-Descombes… - Acta …, 2017 - Springer
Autism spectrum disorder (ASD) has a major impact on the development and social
integration of affected individuals and is the most heritable of psychiatric disorders. An …

[HTML][HTML] The role of the microbiota-gut-brain axis in neuropsychiatric disorders

JS Generoso, VV Giridharan, J Lee… - Brazilian Journal of …, 2020 - SciELO Brasil
The microbiota-gut-brain axis is a bidirectional signaling mechanism between the
gastrointestinal tract and the central nervous system. The complexity of the intestinal …

Changes in the gut microbiota of children with autism spectrum disorder

R Zou, F Xu, Y Wang, M Duan, M Guo… - Autism …, 2020 - Wiley Online Library
Alterations in the gut microbiota may influence gastrointestinal (GI) dysbiosis frequently
reported in individuals with autism spectrum disorder (ASD). In this study, we sequenced the …

Current enlightenment about etiology and pharmacological treatment of autism spectrum disorder

N Eissa, M Al-Houqani, A Sadeq, SK Ojha… - Frontiers in …, 2018 - frontiersin.org
Autistic Spectrum Disorder (ASD) is a complex neurodevelopmental brain disorder
characterized by two core behavioral symptoms, namely impairments in social …

Analysis of gut microbiota profiles and microbe-disease associations in children with autism spectrum disorders in China

M Zhang, W Ma, J Zhang, Y He, J Wang - Scientific reports, 2018 - nature.com
Autism spectrum disorder (ASD) is a set of complex neurodevelopmental disorders. Recent
studies reported that children with ASD have altered gut microbiota profiles compared with …

A systematic review of the valproic-acid-induced rodent model of autism

D Chaliha, M Albrecht, M Vaccarezza… - Developmental …, 2020 - karger.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterised by
repetitive behaviours, cognitive rigidity/inflexibility, and social-affective impairment …

Adult microbiota‐deficient mice have distinct dendritic morphological changes: Differential effects in the amygdala and hippocampus

P Luczynski, SO Whelan, C O'Sullivan… - European Journal of …, 2016 - Wiley Online Library
Increasing evidence implicates the microbiota in the regulation of brain and behaviour.
Germ‐free mice (GF; microbiota deficient from birth) exhibit altered stress hormone …