Cholangiocarcinoma—evolving concepts and therapeutic strategies

SI Ilyas, SA Khan, CL Hallemeier, RK Kelley… - Nature reviews Clinical …, 2018 - nature.com
Cholangiocarcinoma is a disease entity comprising diverse epithelial tumours with features
of cholangiocyte differentiation: cholangiocarcinomas are categorized according to …

Comparative effectiveness of biliary brush cytology and intraductal biopsy for detection of malignant biliary strictures: a systematic review and meta-analysis

U Navaneethan, B Njei, V Lourdusamy… - Gastrointestinal …, 2015 - Elsevier
Background Evaluation of indeterminate biliary strictures typically involves collection and
analysis of tissue or cells. Brush cytology and intraductal biopsies that are routinely …

Epidemiology of cholangiocarcinoma

A Bergquist, E von Seth - Best practice & research Clinical …, 2015 - Elsevier
Cholangiocarcinoma (CCA) is a cancer arising from the intra-or extrahepatic bile ducts and
mainly characterized by its late diagnosis and fatal outcome. CCA is the second most …

Primary sclerosing cholangitis

GM Hirschfield, TH Karlsen, KD Lindor, DH Adams - The Lancet, 2013 - thelancet.com
Primary sclerosing cholangitis is the classic hepatobiliary manifestation of inflammatory
bowel disease and is generally chronic and progressive. Patients frequently present with …

[PDF][PDF] Serum extracellular vesicles contain protein biomarkers for primary sclerosing cholangitis and cholangiocarcinoma

A Arbelaiz, M Azkargorta, M Krawczyk… - …, 2017 - Wiley Online Library
Cholangiocarcinoma (CCA) includes a heterogeneous group of biliary cancers with poor
prognosis. Several conditions, such as primary sclerosing cholangitis (PSC), are risk factors …

Pathogenesis of primary sclerosing cholangitis and advances in diagnosis and management

JE Eaton, JA Talwalkar, KN Lazaridis, GJ Gores… - Gastroenterology, 2013 - Elsevier
Primary sclerosing cholangitis (PSC), first described in the mid-1850s, is a complex liver
disease that is heterogeneous in its presentation. PSC is characterized by chronic …

Single-operator cholangioscopy and targeted biopsies in the diagnosis of indeterminate biliary strictures: a systematic review

U Navaneethan, MK Hasan, V Lourdusamy… - Gastrointestinal …, 2015 - Elsevier
Background and Aims Evaluation of indeterminate biliary strictures by brush cytology and
intraductal biopsies is limited by low sensitivity. The utility of SpyGlass peroral …

Label-free quantification in clinical proteomics

DA Megger, T Bracht, HE Meyer, B Sitek - Biochimica et Biophysica Acta …, 2013 - Elsevier
Nowadays, proteomic studies no longer focus only on identifying as many proteins as
possible in a given sample, but aiming for an accurate quantification of them. Especially in …

Biliary strictures: diagnostic considerations and approach

A Singh, A Gelrud, B Agarwal - Gastroenterology report, 2015 - academic.oup.com
Biliary strictures present a diagnostic challenge, especially when no etiology can be
ascertained after laboratory evaluation, abdominal imaging and endoscopic retrograde …

Peptidomics and proteomics based on CE‐MS as a robust tool in clinical application: The past, the present, and the future

A Latosinska, J Siwy, H Mischak, M Frantzi - Electrophoresis, 2019 - Wiley Online Library
Capillary electrophoresis combined with mass spectrometry (CE‐MS) has been used for
several years for the investigation of proteins and peptides as biomarkers for diagnosis and …