Positive surgical margins after radical prostatectomy: a systematic review and contemporary update

O Yossepowitch, A Briganti, JA Eastham, J Epstein… - European urology, 2014 - Elsevier
Context The clinical significance of positive surgical margins (PSMs) in radical
prostatectomy (RP) specimens and the management of affected patients remain unclear …

Best practices in robot-assisted radical prostatectomy: recommendations of the Pasadena Consensus Panel

F Montorsi, TG Wilson, RC Rosen, TE Ahlering… - European urology, 2012 - Elsevier
CONTEXT: Radical retropubic prostatectomy (RRP) has long been the most common
surgical technique used to treat clinically localized prostate cancer (PCa). More recently …

Postoperative radiotherapy after radical prostatectomy for high-risk prostate cancer: long-term results of a randomised controlled trial (EORTC trial 22911)

M Bolla, H van Poppel, B Tombal, K Vekemans… - The Lancet, 2012 - thelancet.com
Background We report the long-term results of a trial of immediate postoperative irradiation
versus a wait-and-see policy in patients with prostate cancer extending beyond the prostate …

Diagnosis of prostate cancer by desorption electrospray ionization mass spectrometric imaging of small metabolites and lipids

S Banerjee, RN Zare, RJ Tibshirani… - Proceedings of the …, 2017 - National Acad Sciences
Accurate identification of prostate cancer in frozen sections at the time of surgery can be
challenging, limiting the surgeon's ability to best determine resection margins during …

Neurovascular structure-adjacent frozen-section examination (NeuroSAFE) increases nerve-sparing frequency and reduces positive surgical margins in open and …

T Schlomm, P Tennstedt, C Huxhold, T Steuber… - European urology, 2012 - Elsevier
BACKGROUND: Intraoperative frozen-section analysis allows real-time histologic
assessment of surgical margins (SMs) and identification of candidates for nerve-sparing …

First-in-patient study of OTL78 for intraoperative fluorescence imaging of prostate-specific membrane antigen-positive prostate cancer: a single-arm, phase 2a …

JA Stibbe, HA de Barros, DGJ Linders… - The Lancet …, 2023 - thelancet.com
Background Targeted real-time imaging during robot-assisted radical prostatectomy
provides information on the localisation and extent of prostate cancer. We assessed the …

Prognostic value of intraductal carcinoma of the prostate in radical prostatectomy specimens

K Kimura, T Tsuzuki, M Kato, AM Saito, N Sassa… - The …, 2014 - Wiley Online Library
BACKGROUND Intraductal carcinoma of the prostate (IDC‐P) is an adverse prognostic
factor for radical prostatectomy (RP). The endpoint in most IDC‐P studies is increased …

A multinational, multi-institutional study comparing positive surgical margin rates among 22 393 open, laparoscopic, and robot-assisted radical prostatectomy patients

P Sooriakumaran, A Srivastava, SF Shariat, PD Stricker… - European urology, 2014 - Elsevier
Abstract Background Positive surgical margins (PSMs) are a known risk factor for
biochemical recurrence in patients with prostate cancer (PCa) and are potentially affected by …

Positive surgical margins at radical prostatectomy predict prostate cancer specific mortality

JL Wright, BL Dalkin, LD True, WJ Ellis, JL Stanford… - The Journal of …, 2010 - Elsevier
PURPOSE: Positive surgical margins in men undergoing radical prostatectomy for prostate
cancer are associated with an increased risk of biochemical recurrence. Few data are …

Digital frozen sections with fluorescence confocal microscopy during robot-assisted radical prostatectomy: surgical technique

B Rocco, L Sarchi, S Assumma, A Cimadamore… - European Urology, 2021 - Elsevier
Background Robot-assisted radical prostatectomy (RARP) involves a tradeoff between
oncological control and functional outcomes. Intraoperative control of surgical margins …