Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries

D Akaberi, M Pourghasemi Lati… - Antimicrobial Agents …, 2024 - journals.asm.org
In vitro screening of large compound libraries with automated high-throughput screening is
expensive and time-consuming and requires dedicated infrastructures. Conversely, the …

Covalent DNA-Encoded Library Workflow Drives Discovery of SARS-CoV-2 Non-structural Proteins Inhibitors

X Lu, H Hu, L Mei, X Wang, L Xiong, Y Zhu, S Liu… - bioRxiv, 2024 - biorxiv.org
The global coronavirus disease 2019 (COVID-19) pandemic persists, with the ongoing
mutation of the virus. Consequently, the development of inhibitors with diverse binding …