Research progress on phosphatidylinositol 4-kinase inhibitors
G Li, Y Wu, Y Zhang, H Wang, M Li, D He… - Biochemical …, 2024 - Elsevier
Abstract Phosphatidylinositol 4-kinases (PI4Ks) could phosphorylate phosphatidylinositol
(PI) to produce phosphatidylinositol 4-phosphate (PI4P) and maintain its metabolic balance …
(PI) to produce phosphatidylinositol 4-phosphate (PI4P) and maintain its metabolic balance …
Research progress of phosphatidylinositol 4-kinase and its inhibitors in inflammatory diseases
Abstract Phosphatidylinositol 4-kinase (PI4K) is a lipid kinase that can catalyze the transfer
of phosphate group from ATP to the inositol ring of phosphatidylinositol (PtdIns) resulting in …
of phosphate group from ATP to the inositol ring of phosphatidylinositol (PtdIns) resulting in …
Identification of LASSBio-1945 as an inhibitor of SARS-CoV-2 main protease (M PRO) through in silico screening supported by molecular docking and a fragment …
In December 2019, an infectious disease was detected in Wuhan, China, caused by a new
pathogenic coronavirus, named SARS-CoV-2. It spread very rapidly, and on March 11th of …
pathogenic coronavirus, named SARS-CoV-2. It spread very rapidly, and on March 11th of …
A critical analysis of the binding pocket of Plasmodium falciparum Phosphatidylinositol‐4‐kinase enzyme
The Plasmodium falciparum phosphatidylinositol 4‐kinase type III beta (PfPI4KIIIβ), a
protease kinase enzyme, has been shown to be vitally important for the survival of the …
protease kinase enzyme, has been shown to be vitally important for the survival of the …
[HTML][HTML] From Origin to Current Methods: An Overview of Molecular Modeling Applied to Medicinal Chemistry in the Last 30 Years
VN Rocha, CMR Sant'Anna - Journal of the Brazilian Chemical …, 2024 - SciELO Brasil
Molecular modeling soon attracted the attention of Medicinal Chemistry researchers, given
the importance of molecular structure for understanding the mode of action and for …
the importance of molecular structure for understanding the mode of action and for …
LASSBio Chemical Library Diversity and FLT3 New Ligand Identification
LS Franco, RC Maia, EJ Barreiro - Journal of the Brazilian Chemical …, 2024 - SciELO Brasil
This account describes the analysis of the Laboratory of Evaluation and Synthesis of
Bioactive Substances (LASSBio) chemical library as a valuable resource for early drug …
Bioactive Substances (LASSBio) chemical library as a valuable resource for early drug …