Enzymatic noncovalent synthesis

H He, W Tan, J Guo, M Yi, AN Shy, B Xu - Chemical reviews, 2020 - ACS Publications
Enzymatic reactions and noncovalent (ie, supramolecular) interactions are two fundamental
nongenetic attributes of life. Enzymatic noncovalent synthesis (ENS) refers to a process …

The nuclear pore complex: understanding its function through structural insight

M Beck, E Hurt - Nature reviews Molecular cell biology, 2017 - nature.com
Nuclear pore complexes (NPCs) fuse the inner and outer nuclear membranes to form
channels across the nuclear envelope. They are large macromolecular assemblies with a …

Structure and assembly of the nuclear pore complex

B Hampoelz, A Andres-Pons… - Annual review of …, 2019 - annualreviews.org
Nuclear pore complexes (NPCs) mediate nucleocytoplasmic exchange. They are
exceptionally large protein complexes that fuse the inner and outer nuclear membranes to …

Mitotic disassembly and reassembly of nuclear pore complexes

U Kutay, R Jühlen, W Antonin - Trends in Cell Biology, 2021 - cell.com
Nuclear pore complexes (NPCs) are huge protein assemblies within the nuclear envelope
(NE) that serve as selective gates for macromolecular transport between nucleus and …

The nuclear pore complex: birth, life, and death of a cellular behemoth

E Dultz, M Wojtynek, O Medalia, E Onischenko - Cells, 2022 - mdpi.com
Nuclear pore complexes (NPCs) are the only transport channels that cross the nuclear
envelope. Constructed from~ 500–1000 nucleoporin proteins each, they are among the …

Mechanisms of nuclear pore complex assembly–two different ways of building one molecular machine

S Otsuka, J Ellenberg - FEBS letters, 2018 - Wiley Online Library
The nuclear pore complex (NPC) mediates all macromolecular transport across the nuclear
envelope. In higher eukaryotes that have an open mitosis, NPC s assemble at two points in …

Protein phosphatases in the regulation of mitosis

J Nilsson - Journal of Cell Biology, 2019 - rupress.org
The accurate segregation of genetic material to daughter cells during mitosis depends on
the precise coordination and regulation of hundreds of proteins by dynamic phosphorylation …

Phosphatases in mitosis: roles and regulation

M Moura, C Conde - Biomolecules, 2019 - mdpi.com
Mitosis requires extensive rearrangement of cellular architecture and of subcellular
structures so that replicated chromosomes can bind correctly to spindle microtubules and …

Nuclear transport proteins: Structure, function, and disease relevance

Y Yang, L Guo, L Chen, B Gong, D Jia… - Signal Transduction and …, 2023 - nature.com
Proper subcellular localization is crucial for the functioning of biomacromolecules, including
proteins and RNAs. Nuclear transport is a fundamental cellular process that regulates the …

Ndc1 drives nuclear pore complex assembly independent of membrane biogenesis to promote nuclear formation and growth

MS Mauro, G Celma, V Zimyanin, MM Magaj… - Elife, 2022 - elifesciences.org
The nuclear envelope (NE) assembles and grows from bilayer lipids produced at the
endoplasmic reticulum (ER). How ER membrane incorporation coordinates with assembly of …