Management of stroke in neonates and children: a scientific statement from the American Heart Association/American Stroke Association

DM Ferriero, HJ Fullerton, TJ Bernard, L Billinghurst… - Stroke, 2019 - Am Heart Assoc
Purpose—Much has transpired since the last scientific statement on pediatric stroke was
published 10 years ago. Although stroke has long been recognized as an adult health …

Childhood stroke

PB Sporns, HJ Fullerton, S Lee, H Kim, WD Lo… - Nature Reviews …, 2022 - nature.com
Stroke is an important cause of neurological morbidity in children; most survivors have
permanent neurological deficits that affect the remainder of their life. Stroke in childhood, the …

Feasibility, safety, and outcome of endovascular recanalization in childhood stroke: the Save ChildS Study

PB Sporns, R Sträter, J Minnerup, H Wiendl… - JAMA …, 2020 - jamanetwork.com
Importance Randomized clinical trials have shown the efficacy of thrombectomy of large
intracranial vessel occlusions in adults; however, any association of therapy with clinical …

Guidelines for urgent management of stroke in children

MJ Rivkin, TJ Bernard, MM Dowling, C Amlie-Lefond - Pediatric neurology, 2016 - Elsevier
Stroke in children carries lasting morbidity. Once recognized, it is important to evaluate and
treat children with acute stroke efficiently and accurately. All children should receive …

Pediatric arterial ischemic stroke: Epidemiology, risk factors, and management

RJ Felling, LR Sun, EC Maxwell, N Goldenberg… - Blood Cells, Molecules …, 2017 - Elsevier
Pediatric arterial ischemic stroke (AIS) is an uncommon but important cause of neurologic
morbidity in neonates and children, with consequences including hemiparesis, intellectual …

Association between thrombectomy and functional outcomes in pediatric patients with acute ischemic stroke from large vessel occlusion

KD Bhatia, S Chowdhury, I Andrews, R Goetti… - JAMA …, 2023 - jamanetwork.com
Importance Pediatric large vessel occlusion (LVO) stroke has a poor natural history.
However, uptake of mechanical thrombectomy is hindered by a lack of clinical trial data in …

Risk of intracranial hemorrhage following intravenous tPA (tissue-type plasminogen activator) for acute stroke is low in children

C Amlie-Lefond, DWW Shaw, A Cooper… - Stroke, 2020 - Am Heart Assoc
Background and Purpose—Data regarding the safety and efficacy of intravenous tPA (tissue-
type plasminogen activator) in childhood acute arterial ischemic stroke are inadequate. The …

Australian clinical consensus guideline: the diagnosis and acute management of childhood stroke

TL Medley, C Miteff, I Andrews, T Ware… - … Journal of Stroke, 2019 - journals.sagepub.com
Stroke is among the top 10 causes of death in children and survivors carry resulting
disabilities for decades, at substantial cost to themselves and their families. Children are not …

Mechanical thrombectomy in pediatric stroke: systematic review, individual patient data meta-analysis, and case series

K Bhatia, H Kortman, C Blair, G Parker… - Journal of …, 2019 - thejns.org
OBJECTIVE The role of mechanical thrombectomy in pediatric acute ischemic stroke is
uncertain, despite extensive evidence of benefit in adults. The existing literature consists of …

Cerebral ischemia in the developing brain

RM Dietz, AL Dingman… - Journal of Cerebral Blood …, 2022 - journals.sagepub.com
Brain ischemia affects all ages, from neonates to the elderly population, and is a leading
cause of mortality and morbidity. Multiple preclinical rodent models involving different ages …