Protocells: Milestones and recent advances

I Gözen, ES Köksal, I Põldsalu, L Xue, K Spustova… - Small, 2022 - Wiley Online Library
The origin of life is still one of humankind's great mysteries. At the transition between
nonliving and living matter, protocells, initially featureless aggregates of abiotic matter, gain …

Versatile phospholipid assemblies for functional synthetic cells and artificial tissues

X Wang, H Du, Z Wang, W Mu, X Han - Advanced materials, 2021 - Wiley Online Library
The bottom‐up construction of a synthetic cell from nonliving building blocks capable of
mimicking cellular properties and behaviors helps to understand the particular biophysical …

Lipid in chips: a brief review of liposomes formation by microfluidics

G Zhang, J Sun - International journal of nanomedicine, 2021 - Taylor & Francis
Liposomes are ubiquitous tools in biomedical applications, such as drug delivery,
membrane science and artificial cell. Micro-and nanofabrication techniques have …

Microfluidics for biosynthesizing: from droplets and vesicles to artificial cells

Y Ai, R Xie, J Xiong, Q Liang - Small, 2020 - Wiley Online Library
Fabrication of artificial biomimetic materials has attracted abundant attention. As one of the
subcategories of biomimetic materials, artificial cells are highly significant for multiple …

Recent advances in the microfluidic production of functional microcapsules by multiple-emulsion templating

JW Kim, SH Han, YH Choi, WM Hamonangan, Y Oh… - Lab on a Chip, 2022 - pubs.rsc.org
Multiple-emulsion drops serve as versatile templates to design functional microcapsules due
to their core–shell geometry and multiple compartments. Microfluidics has been used for the …

Advanced microfluidic technologies for lipid nano-microsystems from synthesis to biological application

BG Carvalho, BT Ceccato, M Michelon, SW Han… - Pharmaceutics, 2022 - mdpi.com
Microfluidics is an emerging technology that can be employed as a powerful tool for
designing lipid nano-microsized structures for biological applications. Those lipid structures …

Hierarchically molecular imprinted porous particles for biomimetic kidney cleaning

H Chen, F Bian, L Sun, D Zhang, L Shang… - Advanced …, 2020 - Wiley Online Library
Blood purification by adsorption of excessive biomolecules is vital for maintaining human
health. Here, inspired by kidney self‐purification, which removes a number of biomolecules …

Can bottom-up synthetic biology generate advanced drug-delivery systems?

F Lussier, O Staufer, I Platzman, JP Spatz - Trends in Biotechnology, 2021 - cell.com
Creating a magic bullet that can selectively kill cancer cells while sparing nearby healthy
cells remains one of the most ambitious objectives in pharmacology. Nanomedicine, which …

Heterogeneous synthetic vesicles toward artificial cells: engineering structure and composition of membranes for multimodal functionalities

J Shin, BD Cole, T Shan, Y Jang - Biomacromolecules, 2022 - ACS Publications
The desire to develop artificial cells to imitate living cells in synthetic vesicle platforms has
continuously increased over the past few decades. In particular, heterogeneous synthetic …

Capillary‐Based Microfluidics—Coflow, Flow‐Focusing, Electro‐Coflow, Drops, Jets, and Instabilities

J Guerrero, YW Chang, AA Fragkopoulos… - Small, 2020 - Wiley Online Library
Capillary‐based microfluidics is a great technique to produce monodisperse and complex
emulsions and particulate suspensions. In this review, the current understanding of drop and …