Extensive injury of endothelial cells in blood vasculature, especially in the microcirculatory
system, frequently occurs in hosts suffering from sepsis and the accompanied systemic …

Endothelial progenitor cells (EPCs), which are a type of stem cell, have been found to have
strong angiogenic and tissue repair capabilities. Extracellular vesicles (EVs) contain many …

Exosomes are membrane-enclosed vesicles secreted by cells, containing a variety of
biologically active ingredients including proteins, nucleic acids and lipids. In this study, we …

Osteoarthritis (OA) is a degenerative illness that greatly impacts the life quality of patients.
Currently, the therapeutic approaches for OA are very limited in clinical. The extracellular …

Simple Summary In this study, we explore for the first time an innovative tool for organ
preservation aimed to preventing ischemia reperfusion injury (IRI) in marginal kidneys from …

Abstract Endothelial Progenitor Cells (EPCs) are precursor cells of endothelial cells (ECs),
which can differentiate into vascular ECs, protect from endothelial dysfunction and tissue …

Kidney transplantation is the first-choice treatment for end-stage renal disease (ESRD).
Kidney transplant recipients (KTRs) are at higher risk of experiencing a life-threatening …

Podocyte injury is the main clinical pathological feature of diabetic kidney disease (DKD).
The studies showed that DKD is associated with the polarization of macrophages to different …

Physical Exercise (EXR) has been shown to have numerous beneficial effects on various
systems in the human body. It leads to a decrease in the risk of mortality from chronic …

Acute kidney injury (AKI) is a common consequence of sepsis with a mortality rate of up to
40%. The pathogenesis of septic AKI is complex and involves several mechanisms leading …