Artemisinins: pharmacological actions beyond anti-malarial
Artemisinins are a family of sesquiterpene trioxane lactone anti-malarial agents originally
derived from Artemisia annua L. The anti-malarial action of artemisinins involves the …
derived from Artemisia annua L. The anti-malarial action of artemisinins involves the …
[HTML][HTML] Medicinal and mechanistic overview of artemisinin in the treatment of human diseases
Artemisinin (ART) is a bioactive compound isolated from the plant Artemisia annua and has
been traditionally used to treat conditions such as malaria, cancer, viral infections, bacterial …
been traditionally used to treat conditions such as malaria, cancer, viral infections, bacterial …
In vitro efficacy of artemisinin-based treatments against SARS-CoV-2
Effective and affordable treatments for patients suffering from coronavirus disease 2019
(COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
(COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
T follicular helper cells in autoimmune diseases
X Wei, X Niu - Journal of Autoimmunity, 2023 - Elsevier
T follicular helper (Tfh) cells with the phenotype of mainly expressing surface molecules
CXC motif chemokine receptor type 5 (CXCR5), inducible co-stimulator (ICOS), secreting …
CXC motif chemokine receptor type 5 (CXCR5), inducible co-stimulator (ICOS), secreting …
[HTML][HTML] Safety and efficacy of artemisinin-piperaquine for treatment of COVID-19: an open-label, non-randomised and controlled trial
G Li, M Yuan, H Li, C Deng, Q Wang, Y Tang… - International journal of …, 2021 - Elsevier
Background There are no effective therapies for patients with Coronavirus disease-2019
(COVID-19). Methods Forty-one patients with confirmed COVID-19 were enrolled in the …
(COVID-19). Methods Forty-one patients with confirmed COVID-19 were enrolled in the …
Cerebral Malaria and Neuronal Implications of Plasmodium Falciparum Infection: From Mechanisms to Advanced Models
Reorganization of host red blood cells by the malaria parasite Plasmodium falciparum
enables their sequestration via attachment to the microvasculature. This artificially increases …
enables their sequestration via attachment to the microvasculature. This artificially increases …
[HTML][HTML] Current challenges and nanotechnology-based pharmaceutical strategies for the treatment and control of malaria
Malaria is one of the prevalent tropical diseases caused by the parasitic protozoan of the
genus Plasmodium spp. With an estimated 228 million cases, it is a major public health …
genus Plasmodium spp. With an estimated 228 million cases, it is a major public health …
Recent pharmacological advances in the repurposing of artemisinin drugs
Y Meng, N Ma, H Lyu, YK Wong… - Medicinal research …, 2021 - Wiley Online Library
Artemisinins are a family of sesquiterpene lactones originally derived from the sweet
wormwood (Artemisia annua). Beyond their well‐characterized role as frontline antimalarial …
wormwood (Artemisia annua). Beyond their well‐characterized role as frontline antimalarial …
Herbal compounds for rheumatoid arthritis: Literatures review and cheminformatics prediction
X Li, S Zhang - Phytotherapy Research, 2020 - Wiley Online Library
Rheumatoid arthritis (RA) is a systemic disease characterized by autoimmunity, joint
inflammation, and cartilage destruction, which affects 0.5–1% of the population. Many …
inflammation, and cartilage destruction, which affects 0.5–1% of the population. Many …
Therapeutic effects of artesunate on lupus-prone MRL/lpr mice are dependent on T follicular helper cell differentiation and activation of JAK2–STAT3 signaling …
WZ Dang, H Li, B Jiang, KS Nandakumar, KF Liu… - Phytomedicine, 2019 - Elsevier
Background Anti-malarial drug artesunate (ART), a semi-synthetic derivative of artemisnin,
has immunosuppressive effects on several autoimmune diseases, including Systemic lupus …
has immunosuppressive effects on several autoimmune diseases, including Systemic lupus …