Articular chondrocytes are quiescent, fully differentiated cells responsible for the
homeostasis of adult articular cartilage by maintaining cellular survival functions and the fine …

Methylation is the most common posttranscriptional modification in cellular RNAs, which has
been reported to modulate the alteration of RNA structure for initiating relevant functions …

Background Although osteoarthritis (OA) is one of the most prevalent joint disorders,
effective biomarkers to diagnose OA are still unavailable. This study aimed to acquire some …

The purpose of this narrative review is to provide an overview of last year's publications in
the field of genetics, genomics and epigenetics in the osteoarthritis (OA) field. Major themes …

Osteoarthritis (OA) is a chronic musculoskeletal disease characterised by the destruction of
articular cartilage, synovial inflammation and bone remodelling. Disease aetiology is …

Phenotypic variation in skeletal traits and diseases is the product of genetic and
environmental factors. Epigenetic mechanisms include information‐containing factors, other …

Osteoarthritis (OA) is the most common form of arthritis. However, the exact pathogenesis
remains unclear. Emerging evidence shows that N6-methyladenosine (m6A) modification …

Studies have found that RNA-binding proteins (RBPs) are dysfunctional and play a
significant regulatory role in the development of glioma. Based on The Cancer Genome …

DNA methylation is one of the most studied epigenetic mechanisms that play a pivotal role in
regulating gene expression. The epigenetic component is strongly involved in aging-bone …

Meniscus tears are common knee injuries and a major osteoarthritis (OA) risk factor.
Knowledge gaps that limit the development of therapies for meniscus injury and …