It is estimated that infertility affects 8–12% of couples globally, with a male factor being a
primary or contributing cause in approximately 50% of couples. Causes of male subfertility …

Spermatozoon is a motile cell with a special ability to travel through the woman's
reproductive tract and fertilize an oocyte. To reach and penetrate the oocyte, spermatozoa …

Human sperm proteomics research has gained increasing attention lately, which provides
complete information about the functional state of the spermatozoa. Changes in the sperm …

Sperm motility is a prerequisite for achieving pregnancy, and alterations in sperm motility,
along with sperm count and morphology, are commonly observed in subfertile men. The aim …

Proteomic methodologies offer a robust approach to identify and quantify thousands of
proteins from semen components in both fertile donors and infertile patients. These …

Abstract STUDY QUESTION Is histone H4 acetylation (H4ac) altered in the seminiferous
tubules of patients affected by testicular tumours? SUMMARY ANSWER A considerable …

An advanced understanding of sperm function is relevant for evidence-based male fertility
prediction and addressing male infertility. A standard breeding soundness evaluation (BSE) …

Background Although male factor accounts for 40%–50% of unintended childlessness, we
are far from fully understanding the detailed causes. Usually, affected men cannot even be …

For fully differentiated, long lived cells the maintenance of protein homeostasis
(proteostasis) becomes a crucial determinant of cellular function and viability. Neurons are …

Significance: Male reproductive research at molecular level has gained more attention as it
offers the cellular mechanisms and biological pathways implicated in the reproductive …