Male infertility

A Agarwal, S Baskaran, N Parekh, CL Cho, R Henkel… - The Lancet, 2021 - thelancet.com
It is estimated that infertility affects 8–12% of couples globally, with a male factor being a
primary or contributing cause in approximately 50% of couples. Causes of male subfertility …

[HTML][HTML] Current insights and latest updates in sperm motility and associated applications in assisted reproduction

R Dcunha, RS Hussein, H Ananda, S Kumari… - Reproductive …, 2022 - Springer
Spermatozoon is a motile cell with a special ability to travel through the woman's
reproductive tract and fertilize an oocyte. To reach and penetrate the oocyte, spermatozoa …

[HTML][HTML] Proteomic analyses of human sperm cells: understanding the role of proteins and molecular pathways affecting male reproductive health

A Agarwal, MK Panner Selvam, S Baskaran - International Journal of …, 2020 - mdpi.com
Human sperm proteomics research has gained increasing attention lately, which provides
complete information about the functional state of the spermatozoa. Changes in the sperm …

Proteomics of human spermatozoa

J Castillo, A de la Iglesia, M Leiva, M Jodar… - Human …, 2023 - academic.oup.com
Proteomic methodologies offer a robust approach to identify and quantify thousands of
proteins from semen components in both fertile donors and infertile patients. These …

The human sperm proteome—Toward a panel for male fertility testing

T Greither, M Dejung, HM Behre, F Butter, H Herlyn - Andrology, 2023 - Wiley Online Library
Background Although male factor accounts for 40%–50% of unintended childlessness, we
are far from fully understanding the detailed causes. Usually, affected men cannot even be …

[HTML][HTML] Testis-Specific Isoform of Na+-K+ ATPase and Regulation of Bull Fertility

S Tiwari, G Rajamanickam, V Unnikrishnan… - International Journal of …, 2022 - mdpi.com
An advanced understanding of sperm function is relevant for evidence-based male fertility
prediction and addressing male infertility. A standard breeding soundness evaluation (BSE) …

[HTML][HTML] Proteostasis in the male and female germline: a new outlook on the maintenance of reproductive health

SL Cafe, B Nixon, H Ecroyd, JH Martin… - Frontiers in cell and …, 2021 - frontiersin.org
For fully differentiated, long lived cells the maintenance of protein homeostasis
(proteostasis) becomes a crucial determinant of cellular function and viability. Neurons are …

[HTML][HTML] Proteins involved in mitochondrial metabolic functions and fertilization predominate in stallions with better motility

G Gaitskell-Phillips, FE Martín-Cano… - Journal of …, 2021 - Elsevier
Even in stallions with sperm quality within normal reference ranges at ejaculation, subtle
differences in sperm quality exist that in many cases lead to reduced time frames for …

Unraveling the footsteps of proteomics in male reproductive research: a scientometric approach

A Agarwal, S Baskaran, MK Panner Selvam… - Antioxidants & Redox …, 2020 - liebertpub.com
Significance: Male reproductive research at molecular level has gained more attention as it
offers the cellular mechanisms and biological pathways implicated in the reproductive …

Mapping the human sperm proteome–novel insights into reproductive research

MA Miyazaki, RL Guilharducci, P Intasqui… - Expert Review of …, 2023 - Taylor & Francis
Introduction Spermatozoa are highly specialized cells with unique morphology. In addition,
spermatozoa lose a considerable amount of cytoplasm during spermiogenesis, when they …