Robust and efficient processes are needed to establish scientific confidence in new
approach methodologies (NAMs) if they are to be considered for regulatory applications …

New approach methodologies (NAMs) are increasingly being used for regulatory decision
making by agencies worldwide because of their potential to reliably and efficiently produce …

Abstract Background New Approach Methodologies (NAMs) comprise in silico and in vitro
methods applied as alternative to animal testing. Even though NAMs are already fully …

Developmental neurotoxicity (DNT) is a major safety concern for all chemicals of the human
exposome. However, DNT data from animal studies are available for only a small …

Abstract Organ-on-chip (OoC) technology has led to in vitro models with many new
possibilities compared to conventional in vitro and in vivo models. In this review, the …

Four decades of the Human Genome Project and its consequences have shown how the
entrepreneurial state, through significant investment into science, can drive scientific …

Abstract In the European Union, the Chemicals Strategy for Sustainability (CSS) highlights
the need to enhance the identification and assessment of substances of concern while …

In 2012, 20 key questions related to hazard and exposure assessment and environmental
and health risks of pharmaceuticals and personal care products in the natural environment …

Research in the field of environmental sciences currently attracts a lot of attention. As the
pollution of the environment is already pushing the earth beyond its homeostasis state …

EFSA's aim by 2030, is that the Agency and its partners will be equipped for the routine
implementation of human health risk assessment to multiple chemicals, across EFSA's …