Pathophysiology of sickle cell disease

P Sundd, MT Gladwin, EM Novelli - Annual review of pathology …, 2019 - annualreviews.org
Since the discovery of sickle cell disease (SCD) in 1910, enormous strides have been made
in the elucidation of the pathogenesis of its protean complications, which has inspired recent …

Management of sickle cell disease: summary of the 2014 evidence-based report by expert panel members

BP Yawn, GR Buchanan, AN Afenyi-Annan, SK Ballas… - Jama, 2014 - jamanetwork.com
Importance Sickle cell disease (SCD) is a life-threatening genetic disorder affecting nearly
100 000 individuals in the United States and is associated with many acute and chronic …

Guidelines for the primary prevention of stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association

JF Meschia, C Bushnell, B Boden-Albala, LT Braun… - Stroke, 2014 - Am Heart Assoc
The aim of this updated statement is to provide comprehensive and timely evidence-based
recommendations on the prevention of stroke among individuals who have not previously …

[HTML][HTML] Controlled trial of transfusions for silent cerebral infarcts in sickle cell anemia

MR DeBaun, M Gordon, RC McKinstry… - … England Journal of …, 2014 - Mass Medical Soc
Background Silent cerebral infarcts are the most common neurologic injury in children with
sickle cell anemia and are associated with the recurrence of an infarct (stroke or silent …

Guidelines for the primary prevention of stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association

LB Goldstein, CD Bushnell, RJ Adams, LJ Appel… - Stroke, 2011 - Am Heart Assoc
Background and Purpose—This guideline provides an overview of the evidence on
established and emerging risk factors for stroke to provide evidence-based …

Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council: cosponsored by the …

LB Goldstein, R Adams, MJ Alberts, LJ Appel, LM Brass… - Stroke, 2006 - Am Heart Assoc
Background and Purpose—This guideline provides an overview of the evidence on various
established and potential stroke risk factors and provides recommendations for the reduction …

Management of stroke in infants and children: a scientific statement from a Special Writing Group of the American Heart Association Stroke Council and the Council on …

ES Roach, MR Golomb, R Adams, J Biller, S Daniels… - Stroke, 2008 - Am Heart Assoc
Purpose—The purpose of this statement is to review the literature on childhood stroke and to
provide recommendations for optimal diagnosis and treatment. This statement is intended …

Sickle-cell disease

MJ Stuart, RL Nagel - The Lancet, 2004 - thelancet.com
With the global scope of sickle-cell disease, knowledge of the countless clinical
presentations and treatment of this disorder need to be familiar to generalists …

Central nervous system complications and management in sickle cell disease

MR DeBaun, FJ Kirkham - Blood, The Journal of the American …, 2016 - ashpublications.org
With advances in brain imaging and completion of randomized clinical trials (RCTs) for
primary and secondary stroke prevention, the natural history of central nervous system …

[HTML][HTML] Red cell transfusion and alloimmunization in sickle cell disease

GE Linder, ST Chou - Haematologica, 2021 - ncbi.nlm.nih.gov
Red cell transfusion remains a critical component of care for acute and chronic
complications of sickle cell disease. Randomized clinical trials demonstrated the benefits of …